MERCK / MILLIPORESIGMA
Learn how Protacs work for targeted protein degradation to widen the spectrum of targetable proteins Targeted protein degradation (TPD) is an emerging drug discovery strategy that allows access to difficult-to-treat diseases. While traditional small-molecule drugs may only allow access to ~20% of the proteome, degradation techniques may open the door to the other 80%. Proteolysis targeting chimeras (Protacs) are an attractive new means of protein degradation, and work catalytically at sub-stoichiometric levels over an extended length of time. These tools have the potential to widen the spectrum of targetable proteins, including proteins that have proven intractable to traditional approaches.
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Center for Public Health Workforce Development
The environmental toxicology webinar presents the principles and fundamental concepts of toxicology, including the mechanisms of toxicity produced by chemical substances on living organisms and humans. It defines the ADME (absorption, distribution, metabolism, and excretion) process and how it relates to understanding the toxicological effects of environmental substances. The webinar also discusses how toxicology is important in risk assessment and the development of environmental regulations that enforce acceptable exposure levels.
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ChemLinked
Compared with sewage and waste gas, the regulation and control of hazardous waste started late in China. However, with gradual improvements made to the system of sewage and waste gas regulation, the central government has been devoting greater efforts to strengthen the supervision of hazardous waste, introducing and revising a series of relevant regulations and policies. Due to frequent regulatory updates, uncertainties of policy orientation, and regional differences in supervision and law enforcement, enterprises may be confused about specific management requirements, which adds to the difficulty of compliance.
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GoToWebinar
Investment in digital solutions within the petrochemical supply chain is on the rise, yet there appears to be a disconnect between the perceived and actual value of these next-gen blockchains, cloud or AI enabled tools – especially for the owner-operators that are relying on them to help optimize their product’s access to the market. This special webinar event delivers key industry insights on petrochemical supply chain digitalization, to help you cut through the noise, and identify the realistic, cost-efficient digital solutions that will work for your supply chain NOW. • A discussion of the internal and external challenges and hurdles owner operators face when looking to benchmark their current digital systems, define goals for digital investment and harness the value of real-time data points and analytics systems.
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