Managing Waste under the New Hazardous Waste Generator Rule – Strategies for Success

Minor, trace and ultratrace elemental analyses in a variety of geological and petrochemical materials are characterized by difficulties, due to the complexity of their compositions, in obtaining a complete digestion. Traditionally, academic researchers have used a variety of analytical instruments and sample preparation techniques, including open vessel digestions, Parr Bombs, flux fusion, and combustion and closed-vessel microwave digestion to prepare samples for ICP or AA analysis. While these techniques have been somewhat effective, they do pose several limitations for multi-element analysis—temperature and pressure limitations, incomplete digestions, contamination, and time consumption.

Proteolysis-targeting chimeras (PROTACs) are a class of bifunctional molecules which are enabling the development of drugs against targets once considered inaccessible. PROTACs bring a protein of interest into close-proximity to an E3 ubiquitin ligase.

More and more, the process industry is focusing on functional safety. Yet many chemical engineers lack a basic understanding of functional safety for their instrument safety loop.

The world petrochemical and plastics markets have never experienced the conditions that emerged in 2020 and still persist.