Ligand Finding and Chemistry Workflows for Targeted Protein Degradation

Ligand Finding and Chemistry
Proteolysis-targeting chimeras (PROTACs) are a class of bifunctional molecules which are enabling the development of drugs against targets once considered inaccessible.  PROTACs bring a protein of interest into close-proximity to an E3 ubiquitin ligase.
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OTHER ON-DEMAND WEBINARS

UNDERSTANDING THE U.S. EPA HAZARDOUS WASTE GENERATOR IMPROVEMENTS RULE

Verisk 3E

Learn how the Improvement Rule affects your business and yearly reporting as well as how Verisk 3E can be a solution in alleviating the challenges associated with ensuring compliance. Regulatory Background Goals and Objectives How HWGIR affects Hazardous Waste Generators State Adoption Timelines How Verisk 3E Can Help.
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Innovation vs Application: Maximizing Efficiency in Peptide Drug Discovery from a Chemistry Perspective

ACS

The process of drug discovery and development is a path that enlists the expertise of many while in pursuit of the one novel entity that rises above a host of potential candidates. For peptides this can be a daunting task given molecule complexity, physiochemical properties, receptor selectivity and scale-up of material. This presentation will discuss the discovery of our Glucagon agonist and how to use innovative technologies, focused SAR, and effective integration of a unique multidisciplinary team in the drug discovery process.
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The Dust Hazards Analysis Deadline Is Approaching. Are You Ready?

AIChE

Join ioKinetic’s Michelle Murphy as she prepares you to complete the pre-planning, execution and follow-up tasks required by a NFPA-compliant dust hazards analysis.. This 60-minute ioKinetic-sponsored webinar focuses on how to meet the NFPA’s requirements for DHAs. You’ll learn how to generate and gather process safety information— including the appropriate dust characteristics to measure—choose a qualified DHA leader, staff your team, select a methodology to apply, evaluate process operations and building compartments, document the discussion, and follow up. While there is still time, take this opportunity to get up-to-speed on NFPA standards OSHA has referenced in violations and recommendations as generally accepted good engineering practices (RAGAGEP).
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Reducing Chemical Hazards: The First Move

GreenScreen

It is crucial to make informed decisions when choosing chemicals in products, processes and supply chains. Though it seems like an obvious step, identifying and knowing the potential hazards of chemicals is often overlooked or perceived as too complicated or costly to address. Yet companies face brand and financial risk if they are not making informed decisions about the chemicals they use. The List Translator provides a first line of defense against regrettable chemical choices while the in-person training provides you with hands-on practice and ensures you can effectively use the tool in your organization.
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