Catalysis, Chemical Engineering and Technology Virtual

Are you currently exporting chemicals into Central America or have a chemical manufacturing facility set up in Central America? Cristina Caro Tovar, Verisk 3E’s Regulatory Analyst for Latin America, helps you understand the regulatory landscape in the chemical industry for non-GHS Central American countries. This session will provide answers to how chemicals are regulated and managed for classification and labeling. Ms. Caro also reviewed the most recent progress and developments of the proposed regulation for the registration, importation and classification of chemical substances. Countries covered in this webinar will include: Costa Rica, El Salvador, Nicaragua, Honduras and Guatemala

Learn how Protacs work for targeted protein degradation to widen the spectrum of targetable proteins Targeted protein degradation (TPD) is an emerging drug discovery strategy that allows access to difficult-to-treat diseases. While traditional small-molecule drugs may only allow access to ~20% of the proteome, degradation techniques may open the door to the other 80%. Proteolysis targeting chimeras (Protacs) are an attractive new means of protein degradation, and work catalytically at sub-stoichiometric levels over an extended length of time. These tools have the potential to widen the spectrum of targetable proteins, including proteins that have proven intractable to traditional approaches.

Before marketing a new chemical, the manufacturer/importer, in order to meet the various national and international legal requirements, has to submit information in the form of a notification or registration (e.g. phys-chem, toxicological, ecotoxicological data) to support each Government’s risk assessment to determine whether the substance poses an unreasonable risk to the environment and/or human health. Some countries require pre-manufacture/import notification while for many jurisdictions, the chemical notification process is a tiered system requiring subsequent notifications as the annual amount of the imported or manufactured substance increases. Further, there are expanding global initiatives to assess chemicals already in the marketplace and subsequently take action on any chemicals found to be harmful to human health and/or the environment.

Hazardous Communications Standard – “HAZCOM” is a standard developed by OSHA that requires companies to identify substances or chemicals that may cause illness or injury to our employees or the consumer of our products and communicate these hazards through training of employee and providing communications to our employees and the consumers of our products through labeling and Safety Data Sheets (SDS). This OSHA standard is also aligned with the international labeling requirements referred to as the Globally Harmonized System of Classification and Labeling of Chemicals (GHS). This webinar will cover the points of importance to dental laboratories.