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Okayama University research: Innovative method for determining carcinogenicity of chemicals using iPS cells

October 07, 2020 / Prnewswire

In a recent study published in Scientific Reports researchers at Okayama University use stem cell models to show how certain chemical compounds can induce cancer. Stem cells have the unique ability to grow into any kind of cell within the body. A subtype of these, cancer stem cells (CSCs), reside within tumors enabling the aggressive growth of cancer. Researchers at Okayama University have previously converted ordinary stem cells into CSCs by growing them in tumor milieu. Now, for the first time, Professor SENO Masaharu and Dr. Juan Du from Okayama University and colleagues used this model and developed a method to observe the induction of cancer stem cells to identify potential carcinogens and their mechanisms.