Using A Digital Twin to Enable Safe, Reliable and Efficient Design and Operation

Subsea engineering and production present some of the most complex engineering challenges in the energy industry. Deepwater, harsh offshore environments and complex operating conditions make design, installation and reliable operation even more challenging than onshore or platform-based systems. In this white paper we look at the role of engineering simulation across a wide range of aspects related to the full lifecycle of subsea equipment and facilities throughout the operating life.

Spotlight

Cara Therapeutics

Cara Therapeutics is an emerging biotechnology company focused on developing novel therapeutics to treat pain, inflammation and pruritus. Cara possesses both near-term clinical development opportunities combined with proprietary approaches to developing first-in-class novel therapeutics. Cara's most advanced patented compound, CR845, is currently undergoing clinical testing for acute pain and uremic pruritus. This compound possesses analgesic, anti-inflammatory and antipruritic activities appropriate for multiple therapeutic applications. In addition, Cara aims to develop a future pipeline of first-in-class molecules at novel analgesic and anti-inflammatory targets using its proprietary drug screening technology.

OTHER ARTICLES
Chemical Technology

THE BENEFITS OF CHEMICAL FOAMERS, AND HOW BEST TO USE THEM TO MAXIMISE PRODUCTION

Article | June 21, 2021

Downhole fluid build-up coupled with a drop in reservoir pressure can lead to the rapid decline of gas production rates, and can ultimately result in a well ceasing production. While there are many ways to deliquify a well to maximise production, chemical foamers can be incredibly effective and well worth considering. In this blog post, Kevin Lonie shares some of the benefits of using chemical foamers, and provides insights and advice around how best to use them… “Foamers are a much cheaper option than alternative solutions, such as mechanical lifts, and there is very little risk associated with their usage. If a foamer doesn’t work, it won’t make the well worse - so often we see clients giving them a go before opting for more expensive methods, in the hope that they produce the desired results. And we have seen their success over and over again.”

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Chemical Technology

Application of Chromatography in Various Industries is Changing the Game!

Article | May 13, 2021

Used to separate and analyze compounds into their various components— chromatography plays a crucial part not just in the food industry but in the realms of drug testing, forensics, and even quality control in our favourite alcoholic drinks as well. Advanced Chromatography is an analytical technique introduced to the world by chromatography instrument companies to separate and analyze individual chemicals from complex compounds. Recent developments in the biotechnology and pharma industries have created a significant surge in the chromatography market. Read on to find out five fascinating facts about the day-to-day applications of chromatography in various industries and why businesses are looking to invest more in OEM chromatography manufacturing. Why are Industry-Decision Makers Adapting to Chromatography? Liquid Chromatography; A Popular Choice in Drug Testing Today, a lot of drug tests use liquid chromatography-mass spectrometry because it is easy to use, widely available, and gives quick results. LC and LC-MS can be done in almost any testing facility, which is different from other methods. It can be run by people with little training, so a testing facility can hire mostly technicians instead of highly trained scientists, who are harder to find. LC-MS is also very accurate, which means that there are fewer false positives. With liquid chromatography, you can get results in about 10 to 30 minutes, which is very fast. This technology is used by many drug testing labs across the country. It is widely used and trusted for testing drug samples and many other things. Businesses associated with the sports industry are leveraging chromatography to effectively and accurately test athletes for doping or performance-enhancing drugs. Use of HPCL in Pharmaceutical Industries Chromatography is used in the medical and pharmaceutical industries to create vaccines. In addition, chromatography can determine which antibodies best neutralize viruses and diseases. Mapp Biopharmaceutical, Inc. used the chromatography technique to develop the experimental immunization Zmapp to counteract the deadly Ebola virus. And it is still being used today to fight the coronavirus. The pharmaceutical industry has gained enormous success by exclusively using HPLC to obtain precise results during drug trials. The results can be used to analyze finished drug products and their ingredients quantitatively and qualitatively during manufacturing. The Detector in Forensic Science Chromatography methods are a well-established, powerful suite of methodologies in forensic science, from drug busts, murders, and robberies, to the identification of a plethora of chemical compounds that may be present in samples from terrorist incidents. Forensics use gas chromatography to help solve crimes. It helps analyze blood and clothing samples, allowing forensic scientists to investigate who and what was present at a crime scene. In particular instances, chromatography can even help forensic scientists pinpoint the exact whereabouts of the alleged perpetrator and victim before the crime happened. It’s an error-free process. Therefore, it is incredibly helpful in court. Additionally, chromatography is extremely handy in arson investigations. Most fires have a virtual cocktail of different substances. Every compound and substance differs in size and weight. Chromatography helps break down these varying compounds and substances to help determine what exactly started the fire. Liquid Chromatography in Food Industry Liquid chromatography plays a vital role in the food industry nowadays. It absolves and permits the selective removal of a wide variety of flavor and non-flavor-active food ingredients. The USDA, along with other countries, has prioritized rigorous testing of processed meat's contents. For example, in 2013, it was found that horsemeat was being sold as beef without anyone noticing. As a result, the food industry decided to change its analytical techniques. Chromatography quickly became the best way to find out what was in processed meats. High-Performance Liquid Chromatography and mass spectrometry were used to ensure that meat labeled beef was actually beef. In addition, it could tell if horse meat was mixed in with the beef, which helped keep people safe. Bio-Rad Fast Acid Analysis Column in Beverage Testing Not just food, many beverage manufacturers also use chromatography to ensure that each bottle of their product is the same. But, again, consistent taste is the main priority. And knowing the exact content of each bottle is the most proactive way to measure things. The Bio-Rad fast acid analysis column has been successfully used by many companies to quantitatively determine vitamin C in juices, fresh drinks, and powdered drinks. Chromatography Market is Opening New Dimensions in Various Businesses Undoubtedly, technological advancement has created a vigorous need for chromatography devices. According to Verified Market Research, growing at a CAGR of 3.4% from 2020 to 2027, the chromatography market is projected to reach USD 4.73 billion by 2027. The chromatography instrumentation market is currently witnessing huge advancements in the design of columns. This is raising the demand for development of better analytical reagents and resins. Increasing collaborations among the existing players, specifically in the Asian market is another propelling factor for this market. Additionally, emergence of green chromatography, increasing usage of chromatography instruments for monoclonal antibody purification, and usage of nanomaterial in chromatography are also fuelling the growth of this market. Plus, increased government funding in research and development activities is further driving the market growth. With various pharmaceutical and biotechnology companies, chemical, food and beverage, and other industries contributing to its market growth, one thing is for sure— the increase in the chromatography system market is here to stay.

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Chemical Technology

We need a global agreement that sets targets for reducing plastic waste

Article | June 11, 2021

What follows is an entirely personal take on the challenge of plastic waste and does not represent the views of ICIS or any other expert opinion I have sought out. The views are put forward in the spirit of debate as we move forward, as an industry, to solve the crisis of plastic waste.

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IoT in Chemical market trends you Can’t miss in 2020: Here’s What Will Happen in the near future?

Article | April 12, 2020

Global IoT in Chemical market research report provides the newest industry data and industry future trends. It allows you to identify the products and end users driving Revenue growth and profitability. The IoT in Chemical industry report lists the leading competitors and provides the game-changing strategic analysis of the key factors driving the market. The report includes the forecasts by 2020-2028, analysis by 2014-2019, and discussion of important industry trends, market size, market share predictions and profiles of the top IoT in Chemical industry players.

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Spotlight

Cara Therapeutics

Cara Therapeutics is an emerging biotechnology company focused on developing novel therapeutics to treat pain, inflammation and pruritus. Cara possesses both near-term clinical development opportunities combined with proprietary approaches to developing first-in-class novel therapeutics. Cara's most advanced patented compound, CR845, is currently undergoing clinical testing for acute pain and uremic pruritus. This compound possesses analgesic, anti-inflammatory and antipruritic activities appropriate for multiple therapeutic applications. In addition, Cara aims to develop a future pipeline of first-in-class molecules at novel analgesic and anti-inflammatory targets using its proprietary drug screening technology.

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Chemical Management

LyondellBasell & MSI Technology, LLC Collaborate on Innovative Consumer Packaging

LyondellBasell | February 02, 2024

LyondellBasell and MSI Technology, LLC announced they have entered into an agreement for MSI Technology to serve the LyondellBasell Polybutene-1 (PB-1) resin line into consumer packaging applications for North America. MSI Technology is also the sales representative for the LyondellBasell Plexar product line. The expansion of the relationship is a strategic fit relative to the markets MSI Technology serves today. MSI Technology will use its technical sales approach combined with its current specialty product portfolio to enhance offerings to customers in consumer packaging. LyondellBasell PB-1 resins are commonly used in consumer packaging applications for easy-open packaging and film modification for seal initiation temperature providing Broad seal-peel temperature range Consistent and reproducible peel performance Adjustable peel force to end-use requirements Similar initiation and propagation peel force "Whitening" with "Smooth & Clean" peel surface Good seal integrity Easy processability Usable in blown film, cast film, extrusion coating and sheet extrusion "At LyondellBasell, we're passionate about creating solutions for everyday sustainable living," said Palmer Giddings, vice president Polymers at LyondellBasell. "Collaborating with MSI Technology on innovative packaging solutions is a major step forward in achieving that goal." "We are thrilled to expand our collaboration with LyondellBasell," said Brian McCaghy, president of MSI Technology. "The PB-1 resins align perfectly with our mission to provide specialty polymers and solutions to the packaging industry." The PB-1 resin line is part of MSI Technology's product offerings. The company also provides clients with access to dedicated sales and technical service specialists who provide guidance on technical resin selection to meet customer requirements. About LyondellBasell We are LyondellBasell – a leader in the global chemical industry creating solutions for everyday sustainable living. Through advanced technology and focused investments, we are enabling a circular and low carbon economy. Across all we do, we aim to unlock value for our customers, investors and society. As one of the world's largest producers of polymers and a leader in polyolefin technologies, we develop, manufacture and market high-quality and innovative products for applications ranging from sustainable transportation and food safety to clean water and quality healthcare. About MSI Technology, LLC MSI Technology specializes in the sales, marketing, and development of specialty polymers. Our product lines include: Plexar tie-layer adhesives (manufactured by LyondellBasell), SPS peelable sealants, and SpeciPurge purging compound. MSI Technology and its sister company, Soarus LLC, are located in Arlington Heights, IL. Soarus markets Soarnol™), ethylene vinyl alcohol copolymer (EVOH), (manufactured by Mitsubishi Chemical Group) into North and Latin America. The two companies together provide sales and technical service for specialty polymers focused on the packaging market.

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Chemical Technology

Pall Corporation Introduces SepraLYTE™ Liquid/Gas Coalescers for Green Hydrogen Production

Pall Corporation | January 15, 2024

Pall Corporation, a leading provider of filtration, separation and purification solutions, introduces SepraLYTE™ liquid/gas coalescers, an innovative solution designed to meet the increasing demand for efficient separation of electrolyte aerosols from gas in green hydrogen production processes. Leveraging advanced separation technology, SepraLYTE coalescers excel in the separation of water or electrolyte aerosols (30% potassium hydroxide solution) from hydrogen, ensuring the purity of hydrogen produced from electrolysis processes. They are highly suitable for a wide range of separation applications where minimal pressure drop is crucial for downstream processes. "Our new SepraLYTE coalescers represent Pall's commitment to serving our customers in energy transition markets. Pall continues to innovate to address new and challenging customer needs in fast growing markets like green hydrogen," said Greg Sears, Vice President and General Manager of Pall's Fluid Technologies and Asset Protection business unit. "Pall's coalescers enable our customers to optimize their plant design, maximize the lifetime of their critical equipment and improve overall efficiency, reliability and output," said Sears. These coalescers feature Pall's proprietary melt blown media technology, which achieves outstanding liquid mist separation with low differential pressure. The compact design incorporates coalescer media that ensures compatibility with various chemical applications. Other key advantages of SepraLYTE liquid/gas coalescers is the ease of maintenance, compact size and waste reduction. Utilizing SepraLYTE liquid/gas coalescers, customers gain significant advantages over conventional separation products. These advantages include reliable, consistent and verifiable separation performance, high gas flow and liquid removal in a compact cartridge, which allow for smaller systems with low capital, operating, and maintenance costs. About Pall Corporation Pall Corporation is a filtration, separation and purification leader providing solutions to meet the critical fluid management needs of customers across the broad spectrum of industries. Pall collaborates with customers to advance health, safety, and environmentally responsible technologies. The Company's engineered products enable process and product innovation and minimize emissions and waste.

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Chemical Management

Charter Next Generation Launches GreenArrow™ Cavitated Recycle-Ready PE Films For Confectionery Applications Using Void Technologies'

Charter Next Generation | January 30, 2024

Charter Next Generation (CNG), a leading provider of sustainable films, announced that it has expanded its GreenArrow portfolio with a new line of cavitated polyethylene (PE) films. Developed in collaboration with VOID Technologies (VOID), the new recycle-ready films meet the rapidly growing demand for flow wrap and confectionery applications. Using VOID's patented VO+™ PE Voiding Agent Masterbatch and Machine Direction Orientation (MDO) film processing, CNG has successfully developed high-performing PE film structures that are opaque yet compatible with existing PE recycling streams making more packaging suitable for recycling. Adoption of MDO PE film is a rapidly growing industry trend as it enables recyclable, high-performing flexible packaging. By using VO+ Masterbatch, CNG can now produce thin gauge voided MDO PE films that offer a combination of low density and high opacity not achievable with mineral additives such as TiO2 pigments or CaCO3 cavitation agents. This innovation creates a unique PE-based recycle-ready alternative to conventional PP-based substrates that often require biaxial orientation. "CNG continues to raise the bar and re-invent packaging with a sustainability-first mindset. Using VOID's patented VO+ technology enables us to achieve the high opacity, ease of processing, and recycle-ready performance we are targeting for these films. This in turn allows our customers to reduce their use of virgin materials and process their packaging in existing polyethylene film recycling streams," said Brent Greiner, Vice-President of Technology at Charter Next Generation. The VO+ PE Masterbatch is added to PE resin to create nano and micro-scale voids, reducing density and creating high levels of opacity via light scattering through the voided structure. VOID's latest VO+ PE Masterbatch product is compliant with direct food contact standards in North America and Europe and has passed key recycling standards. James Gibson, CEO of VOID Technologies, commented, "CNG is a highly innovative and forward-thinking company. We are delighted with this collaboration and to be part of launching this new generation of recycle-ready voided PE films. As we look to the future, we are excited to be working with CNG across a range of projects that directly address sustainability and recycling targets." About Charter Next Generation Charter Next Generation (CNG) is North America's leading producer of highly engineered solutions used in the food, consumer, healthcare, and industrial markets. Committed to a sustainability-first approach, CNG leverages material science to engineer materials that help companies meet and exceed their sustainability goals. Known for world-class manufacturing capabilities and an innovation-driven approach, CNG operates fifteen facilities and employs over 2,200 employees and is a proud partner of Ownership Works®—a nonprofit partnering with companies to enable shared ownership, granting employees a stake in the value they create. About VOID Technologies VOID is a materials science company accelerating the transition to more sustainable plastics and packaging. The company combines its VO+ cavitation technology and R&D labs to help plastic and packaging companies rapidly develop new innovative products with a reduced environmental footprint. VOID's extensively patented VO+ technology was first conceived as part of a research initiative at Kimberly-Clark. Soon after, in 2015, VOID was launched as an independent company. Today, VOID has R&D labs and a compound manufacturing facility based in Neenah, Wisconsin (USA) and has commercial teams in Canada, France, and the UK.

Read More

Chemical Management

LyondellBasell & MSI Technology, LLC Collaborate on Innovative Consumer Packaging

LyondellBasell | February 02, 2024

LyondellBasell and MSI Technology, LLC announced they have entered into an agreement for MSI Technology to serve the LyondellBasell Polybutene-1 (PB-1) resin line into consumer packaging applications for North America. MSI Technology is also the sales representative for the LyondellBasell Plexar product line. The expansion of the relationship is a strategic fit relative to the markets MSI Technology serves today. MSI Technology will use its technical sales approach combined with its current specialty product portfolio to enhance offerings to customers in consumer packaging. LyondellBasell PB-1 resins are commonly used in consumer packaging applications for easy-open packaging and film modification for seal initiation temperature providing Broad seal-peel temperature range Consistent and reproducible peel performance Adjustable peel force to end-use requirements Similar initiation and propagation peel force "Whitening" with "Smooth & Clean" peel surface Good seal integrity Easy processability Usable in blown film, cast film, extrusion coating and sheet extrusion "At LyondellBasell, we're passionate about creating solutions for everyday sustainable living," said Palmer Giddings, vice president Polymers at LyondellBasell. "Collaborating with MSI Technology on innovative packaging solutions is a major step forward in achieving that goal." "We are thrilled to expand our collaboration with LyondellBasell," said Brian McCaghy, president of MSI Technology. "The PB-1 resins align perfectly with our mission to provide specialty polymers and solutions to the packaging industry." The PB-1 resin line is part of MSI Technology's product offerings. The company also provides clients with access to dedicated sales and technical service specialists who provide guidance on technical resin selection to meet customer requirements. About LyondellBasell We are LyondellBasell – a leader in the global chemical industry creating solutions for everyday sustainable living. Through advanced technology and focused investments, we are enabling a circular and low carbon economy. Across all we do, we aim to unlock value for our customers, investors and society. As one of the world's largest producers of polymers and a leader in polyolefin technologies, we develop, manufacture and market high-quality and innovative products for applications ranging from sustainable transportation and food safety to clean water and quality healthcare. About MSI Technology, LLC MSI Technology specializes in the sales, marketing, and development of specialty polymers. Our product lines include: Plexar tie-layer adhesives (manufactured by LyondellBasell), SPS peelable sealants, and SpeciPurge purging compound. MSI Technology and its sister company, Soarus LLC, are located in Arlington Heights, IL. Soarus markets Soarnol™), ethylene vinyl alcohol copolymer (EVOH), (manufactured by Mitsubishi Chemical Group) into North and Latin America. The two companies together provide sales and technical service for specialty polymers focused on the packaging market.

Read More

Chemical Technology

Pall Corporation Introduces SepraLYTE™ Liquid/Gas Coalescers for Green Hydrogen Production

Pall Corporation | January 15, 2024

Pall Corporation, a leading provider of filtration, separation and purification solutions, introduces SepraLYTE™ liquid/gas coalescers, an innovative solution designed to meet the increasing demand for efficient separation of electrolyte aerosols from gas in green hydrogen production processes. Leveraging advanced separation technology, SepraLYTE coalescers excel in the separation of water or electrolyte aerosols (30% potassium hydroxide solution) from hydrogen, ensuring the purity of hydrogen produced from electrolysis processes. They are highly suitable for a wide range of separation applications where minimal pressure drop is crucial for downstream processes. "Our new SepraLYTE coalescers represent Pall's commitment to serving our customers in energy transition markets. Pall continues to innovate to address new and challenging customer needs in fast growing markets like green hydrogen," said Greg Sears, Vice President and General Manager of Pall's Fluid Technologies and Asset Protection business unit. "Pall's coalescers enable our customers to optimize their plant design, maximize the lifetime of their critical equipment and improve overall efficiency, reliability and output," said Sears. These coalescers feature Pall's proprietary melt blown media technology, which achieves outstanding liquid mist separation with low differential pressure. The compact design incorporates coalescer media that ensures compatibility with various chemical applications. Other key advantages of SepraLYTE liquid/gas coalescers is the ease of maintenance, compact size and waste reduction. Utilizing SepraLYTE liquid/gas coalescers, customers gain significant advantages over conventional separation products. These advantages include reliable, consistent and verifiable separation performance, high gas flow and liquid removal in a compact cartridge, which allow for smaller systems with low capital, operating, and maintenance costs. About Pall Corporation Pall Corporation is a filtration, separation and purification leader providing solutions to meet the critical fluid management needs of customers across the broad spectrum of industries. Pall collaborates with customers to advance health, safety, and environmentally responsible technologies. The Company's engineered products enable process and product innovation and minimize emissions and waste.

Read More

Chemical Management

Charter Next Generation Launches GreenArrow™ Cavitated Recycle-Ready PE Films For Confectionery Applications Using Void Technologies'

Charter Next Generation | January 30, 2024

Charter Next Generation (CNG), a leading provider of sustainable films, announced that it has expanded its GreenArrow portfolio with a new line of cavitated polyethylene (PE) films. Developed in collaboration with VOID Technologies (VOID), the new recycle-ready films meet the rapidly growing demand for flow wrap and confectionery applications. Using VOID's patented VO+™ PE Voiding Agent Masterbatch and Machine Direction Orientation (MDO) film processing, CNG has successfully developed high-performing PE film structures that are opaque yet compatible with existing PE recycling streams making more packaging suitable for recycling. Adoption of MDO PE film is a rapidly growing industry trend as it enables recyclable, high-performing flexible packaging. By using VO+ Masterbatch, CNG can now produce thin gauge voided MDO PE films that offer a combination of low density and high opacity not achievable with mineral additives such as TiO2 pigments or CaCO3 cavitation agents. This innovation creates a unique PE-based recycle-ready alternative to conventional PP-based substrates that often require biaxial orientation. "CNG continues to raise the bar and re-invent packaging with a sustainability-first mindset. Using VOID's patented VO+ technology enables us to achieve the high opacity, ease of processing, and recycle-ready performance we are targeting for these films. This in turn allows our customers to reduce their use of virgin materials and process their packaging in existing polyethylene film recycling streams," said Brent Greiner, Vice-President of Technology at Charter Next Generation. The VO+ PE Masterbatch is added to PE resin to create nano and micro-scale voids, reducing density and creating high levels of opacity via light scattering through the voided structure. VOID's latest VO+ PE Masterbatch product is compliant with direct food contact standards in North America and Europe and has passed key recycling standards. James Gibson, CEO of VOID Technologies, commented, "CNG is a highly innovative and forward-thinking company. We are delighted with this collaboration and to be part of launching this new generation of recycle-ready voided PE films. As we look to the future, we are excited to be working with CNG across a range of projects that directly address sustainability and recycling targets." About Charter Next Generation Charter Next Generation (CNG) is North America's leading producer of highly engineered solutions used in the food, consumer, healthcare, and industrial markets. Committed to a sustainability-first approach, CNG leverages material science to engineer materials that help companies meet and exceed their sustainability goals. Known for world-class manufacturing capabilities and an innovation-driven approach, CNG operates fifteen facilities and employs over 2,200 employees and is a proud partner of Ownership Works®—a nonprofit partnering with companies to enable shared ownership, granting employees a stake in the value they create. About VOID Technologies VOID is a materials science company accelerating the transition to more sustainable plastics and packaging. The company combines its VO+ cavitation technology and R&D labs to help plastic and packaging companies rapidly develop new innovative products with a reduced environmental footprint. VOID's extensively patented VO+ technology was first conceived as part of a research initiative at Kimberly-Clark. Soon after, in 2015, VOID was launched as an independent company. Today, VOID has R&D labs and a compound manufacturing facility based in Neenah, Wisconsin (USA) and has commercial teams in Canada, France, and the UK.

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