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Pulmonary toxicity – a challenge for drug and chemical development

Despite the common assumption that adverse drug reactions only affect the kidney and liver, more than 600 medications inducing lung toxicity have been reported.1 Lungs are susceptible to toxicity due to their large surface area and metabolism of certain substances2, such as antibiotics and anti-inflammatories, and specialist drugs targeting the cardiovascular system and tumours. This has resulted in 4-10% of patients developing pulmonary toxicity.

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Petrochemical Supplying Co

Petro Chemical Supplying Company is a global Group based in Iran which manufactures and provides chemical and raw material in different cases with deep industrial experiences. Since 2002 our purpose has been founded on the sourcing and development of competitive chemical supply originating in different kind of production with the best quality.

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Chemical Management

THE BENEFITS OF CHEMICAL FOAMERS, AND HOW BEST TO USE THEM TO MAXIMISE PRODUCTION

Article | July 14, 2022

Downhole fluid build-up coupled with a drop in reservoir pressure can lead to the rapid decline of gas production rates, and can ultimately result in a well ceasing production. While there are many ways to deliquify a well to maximise production, chemical foamers can be incredibly effective and well worth considering. In this blog post, Kevin Lonie shares some of the benefits of using chemical foamers, and provides insights and advice around how best to use them… “Foamers are a much cheaper option than alternative solutions, such as mechanical lifts, and there is very little risk associated with their usage. If a foamer doesn’t work, it won’t make the well worse - so often we see clients giving them a go before opting for more expensive methods, in the hope that they produce the desired results. And we have seen their success over and over again.”

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Chemical Technology

Petrochemical buyers, after a very difficult pandemic, can gain from China-driven deflation

Article | July 20, 2022

BUYERS OF polypropylene (PP) and other polymers and petrochemicals have had an incredibly difficult pandemic. Firstly, the converters and brand owners expected doom and gloom last March. At the time it seemed logical to expect a cratering of demand as the global economy pretty much imploded. Just looking at forecasts for GDP, parallels were drawn with the Global Financial Crisis when collapses in growth led to a cratering of polymers demand. The US is a good example where PP demand declined by 12% in 2008 over 2007. Demand then fell by a further 5% in 2009 over 2008.But what we all missed was the complete dislocation of polymers and petrochemicals demand from GDP. As economies registered historic declines, consumption went up. PP demand went through the roof, firstly for food packaging and hygiene applications.Then consumption for the durable goods made from PP also smashed through the rafters as we bought white goods (PP is used to make components of washing machines), consumer electronics (PP is used to make some electronic components) and carpets (PP fibres are used here).

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Chemical Technology

Southeast polyolefins demand growth could be negative again in 2021

Article | June 6, 2022

BEFORE the pandemic, GDP growth rates in the developing world were always higher than in developed economies.And because developing economies had much lower levels of petrochemicals consumption than their rich counterparts, it meant that the multiples over GDP were higher than in the rich word, where consumption was pretty much saturated. For instance, polyethylene (PE) demand in a developed country such as Germany might have grown at 0.3% times GDP whereas in Indonesia the growth could have been one or more times higher than the rate of growth in GDP.But as The Economist wrote in this 11 July article: “In 2021 the poorest countries, which are desperately short of vaccines, are forecast to grow more slowly than rich countries for only the third time in 25 years.” Might the multiples over GDP growth also be adversely affected in the developing world, trending lower than the historic norms? They will almost certainly remain higher than the rich countries. But here is the thing: as millions more people are pushed back into extreme poverty by the pandemic or are denied the opportunity to achieve middle-income status, I believe that developing-world multiples may well decline.Escaping extreme poverty means being able to, say, afford a whole bottle of shampoo for the first time rather than a single-serve sachet, thereby raising per capita polymers consumption.

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Chemical Management

Boom in petrochemicals demand guaranteed but we must grow sustainably

Article | June 3, 2021

ONE OF THE GREATEST achievements of the last 30 years has been the fall in the number of people living in extreme poverty.In 1999, 1.9bn of the world’s population were living on less than $1.90, the Word Bank’s definition of extreme poverty. Despite setbacks caused by the pandemic, this had fallen to 698m by October 2020. Income levels alone are not enough to escape the life-threatening agony of extreme poverty. There is no point in having money if the essential goods and services to spend your money on are not available. Critical to poverty alleviation has been sufficient supply of all the things that people in the rich world take for granted. The raw materials to make the vast majority of manufactured goods include petrochemicals and polymers. Nearly all the major manufacturing chains would not have been able to function without petrochemicals. Think of medical equipment, syringes, blood bags, hospital gowns, face masks, pill bottles and medicine blister packs. None of the above could have been produced without petrochemicals. As people emerged out of extreme poverty and as economies became wealthier, modern-day medical services became more widely available.

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Chemical Management

Key Trends in the Digital Transformation of the Chemical Industry

Article | July 14, 2022

Downhole fluid build-up coupled with a drop in reservoir pressure can lead to the rapid decline of gas production rates, and can ultimately result in a well ceasing production. While there are many ways to deliquify a well to maximise production, chemical foamers can be incredibly effective and well worth considering. In this blog post, Kevin Lonie shares some of the benefits of using chemical foamers, and provides insights and advice around how best to use them… “Foamers are a much cheaper option than alternative solutions, such as mechanical lifts, and there is very little risk associated with their usage. If a foamer doesn’t work, it won’t make the well worse - so often we see clients giving them a go before opting for more expensive methods, in the hope that they produce the desired results. And we have seen their success over and over again.”

Read More
Chemical Technology

Ways Your Chemical Company Can Benefit From Digitization

Article | July 20, 2022

BUYERS OF polypropylene (PP) and other polymers and petrochemicals have had an incredibly difficult pandemic. Firstly, the converters and brand owners expected doom and gloom last March. At the time it seemed logical to expect a cratering of demand as the global economy pretty much imploded. Just looking at forecasts for GDP, parallels were drawn with the Global Financial Crisis when collapses in growth led to a cratering of polymers demand. The US is a good example where PP demand declined by 12% in 2008 over 2007. Demand then fell by a further 5% in 2009 over 2008.But what we all missed was the complete dislocation of polymers and petrochemicals demand from GDP. As economies registered historic declines, consumption went up. PP demand went through the roof, firstly for food packaging and hygiene applications.Then consumption for the durable goods made from PP also smashed through the rafters as we bought white goods (PP is used to make components of washing machines), consumer electronics (PP is used to make some electronic components) and carpets (PP fibres are used here).

Read More
Chemical Technology

Organic Catalyst Boasts Big Benefits

Article | June 6, 2022

BEFORE the pandemic, GDP growth rates in the developing world were always higher than in developed economies.And because developing economies had much lower levels of petrochemicals consumption than their rich counterparts, it meant that the multiples over GDP were higher than in the rich word, where consumption was pretty much saturated. For instance, polyethylene (PE) demand in a developed country such as Germany might have grown at 0.3% times GDP whereas in Indonesia the growth could have been one or more times higher than the rate of growth in GDP.But as The Economist wrote in this 11 July article: “In 2021 the poorest countries, which are desperately short of vaccines, are forecast to grow more slowly than rich countries for only the third time in 25 years.” Might the multiples over GDP growth also be adversely affected in the developing world, trending lower than the historic norms? They will almost certainly remain higher than the rich countries. But here is the thing: as millions more people are pushed back into extreme poverty by the pandemic or are denied the opportunity to achieve middle-income status, I believe that developing-world multiples may well decline.Escaping extreme poverty means being able to, say, afford a whole bottle of shampoo for the first time rather than a single-serve sachet, thereby raising per capita polymers consumption.

Read More
Chemical Management

Boom in petrochemicals demand guaranteed but we must grow sustainably

Article | June 3, 2021

ONE OF THE GREATEST achievements of the last 30 years has been the fall in the number of people living in extreme poverty.In 1999, 1.9bn of the world’s population were living on less than $1.90, the Word Bank’s definition of extreme poverty. Despite setbacks caused by the pandemic, this had fallen to 698m by October 2020. Income levels alone are not enough to escape the life-threatening agony of extreme poverty. There is no point in having money if the essential goods and services to spend your money on are not available. Critical to poverty alleviation has been sufficient supply of all the things that people in the rich world take for granted. The raw materials to make the vast majority of manufactured goods include petrochemicals and polymers. Nearly all the major manufacturing chains would not have been able to function without petrochemicals. Think of medical equipment, syringes, blood bags, hospital gowns, face masks, pill bottles and medicine blister packs. None of the above could have been produced without petrochemicals. As people emerged out of extreme poverty and as economies became wealthier, modern-day medical services became more widely available.

Read More
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Spotlight

Petrochemical Supplying Co

Petro Chemical Supplying Company is a global Group based in Iran which manufactures and provides chemical and raw material in different cases with deep industrial experiences. Since 2002 our purpose has been founded on the sourcing and development of competitive chemical supply originating in different kind of production with the best quality.

Related News

NGOs file suit over transparency of TSCA new chemicals programme

Chemical Watch | March 18, 2020

A coalition of NGOs has sued the US EPA over an alleged lack of transparency in the TSCA new chemicals programme, which "thwart[s] the ability of the public to be informed and to provide input". According to a complaint filed by five environmental nonprofits in federal court today, the EPA has operated its TSCA premanufacture review process in a "black box, denying the public information to which they are legally entitled". Having access to timely information, they contend, is necessary to ensure the members they represent "are able to provide input on the potential risks of new chemicals and the need for protections from those risks prior to completion of EPA’s reviews." And they therefore have asked the court to ensure that the EPA complies with TSCA’s disclosure provisions, including by requiring that it:

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ACC to Trump, governors: Keep chemical industry going during coronavirus crisis

S&P Global | March 18, 2020

The US chemical industry's trade group told President Donald Trump and state governors this week that its sector must maintain operations as the coronavirus outbreak spreads to ensure supply of chemicals needed for disinfectants, plastics for food preservation and medical equipment, and staples like diapers and soap. "The role of chemistry is particularly important today, as chemicals enable countless products that will be needed to support good hygiene and treat those who are infected with the coronavirus in the weeks and months ahead," American Chemistry Council President and CEO Chris Jahn said in a letter to Trump and governors late Tuesday. Efforts to hinder the spread of coronavirus have included cancellations of major sporting events, concerts, conferences, parades, and other large gatherings, as well as closures of bars and limiting restaurants to takeout and deliveries. Companies have increasingly sent employees to work from their homes, while hospitals, grocery stores, and drug stores work to keep up with demand for care and products.

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How small chemical company leaders are dealing with the coronavirus

C&EN | March 17, 2020

As measures to contain the coronavirus—SARS-CoV-2—sweep across the US, the heads of privately owned chemical and instrument companies find themselves in uncharted territory trying to keep their companies going and their employees safe. C&EN reached out to CEOs of several such firms to learn what they are doing to keep business moving forward. We heard stories about setbacks, as expected supplies didn’t come through, but also small triumphs, as needed safety equipment was finally found. Overall, these leaders are keeping a close eye on supplies while planning for the real possibility that orders will drop in the coming months. Keeping staff healthy and maintaining continuity in customer service are the top priorities at Boron Specialties. “We are a pretty small facility, seven people &on-site&, so as best as we can we’re isolating,” CEO and founder Beth Bosley says.

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NGOs file suit over transparency of TSCA new chemicals programme

Chemical Watch | March 18, 2020

A coalition of NGOs has sued the US EPA over an alleged lack of transparency in the TSCA new chemicals programme, which "thwart[s] the ability of the public to be informed and to provide input". According to a complaint filed by five environmental nonprofits in federal court today, the EPA has operated its TSCA premanufacture review process in a "black box, denying the public information to which they are legally entitled". Having access to timely information, they contend, is necessary to ensure the members they represent "are able to provide input on the potential risks of new chemicals and the need for protections from those risks prior to completion of EPA’s reviews." And they therefore have asked the court to ensure that the EPA complies with TSCA’s disclosure provisions, including by requiring that it:

Read More

ACC to Trump, governors: Keep chemical industry going during coronavirus crisis

S&P Global | March 18, 2020

The US chemical industry's trade group told President Donald Trump and state governors this week that its sector must maintain operations as the coronavirus outbreak spreads to ensure supply of chemicals needed for disinfectants, plastics for food preservation and medical equipment, and staples like diapers and soap. "The role of chemistry is particularly important today, as chemicals enable countless products that will be needed to support good hygiene and treat those who are infected with the coronavirus in the weeks and months ahead," American Chemistry Council President and CEO Chris Jahn said in a letter to Trump and governors late Tuesday. Efforts to hinder the spread of coronavirus have included cancellations of major sporting events, concerts, conferences, parades, and other large gatherings, as well as closures of bars and limiting restaurants to takeout and deliveries. Companies have increasingly sent employees to work from their homes, while hospitals, grocery stores, and drug stores work to keep up with demand for care and products.

Read More

How small chemical company leaders are dealing with the coronavirus

C&EN | March 17, 2020

As measures to contain the coronavirus—SARS-CoV-2—sweep across the US, the heads of privately owned chemical and instrument companies find themselves in uncharted territory trying to keep their companies going and their employees safe. C&EN reached out to CEOs of several such firms to learn what they are doing to keep business moving forward. We heard stories about setbacks, as expected supplies didn’t come through, but also small triumphs, as needed safety equipment was finally found. Overall, these leaders are keeping a close eye on supplies while planning for the real possibility that orders will drop in the coming months. Keeping staff healthy and maintaining continuity in customer service are the top priorities at Boron Specialties. “We are a pretty small facility, seven people &on-site&, so as best as we can we’re isolating,” CEO and founder Beth Bosley says.

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