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Pulmonary toxicity – a challenge for drug and chemical development

March 11, 2020 | 201 views

Despite the common assumption that adverse drug reactions only affect the kidney and liver, more than 600 medications inducing lung toxicity have been reported.1 Lungs are susceptible to toxicity due to their large surface area and metabolism of certain substances2, such as antibiotics and anti-inflammatories, and specialist drugs targeting the cardiovascular system and tumours. This has resulted in 4-10% of patients developing pulmonary toxicity.

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Vical develops biopharmaceutical products for the prevention and treatment of chronic or life-threatening infectious diseases, based on our patented DNA delivery technologies and other therapeutic approaches. Headquartered in San Diego, CA, Vical is independently pioneering the development of paradigm-changing therapies, and is partnering with key industry leaders.

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