Maintaining chemical hazard control measures

WALTER INGLES | January 30, 2019 | 302 views

You’ve identified and assessed the chemical hazards at your workplace: you’ve introduced hazard control measures. But is your workplace 100% safety compliant? This blog is about the systems you’ll need to have in place to ensure chemical compliance and to help you understand that good risk management is always a journey and never a destination.

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FourQuest Energy

With our industry-leading fleet of equipment, experienced personnel and engineering capabilities we provide our clients the most efficient turnaround and maintenance programs, nitrogen when you need it, proven specialty chemicals, and a full range of pre-commissioning and commissioning services. You can trust us for all your industrial cleaning needs at oil and gas, refinery, petrochemical and many other industrial facilities across North America.

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Chemical Management

Organic Catalyst Boasts Big Benefits

Article | July 22, 2021

An enzyme-mimicking catalyst opens a new route to important organic molecules such as glycolic acid and amino acids from pyruvate, report researchers in Japan. Moreover, the new catalyst is cheaper, more stable, safer and more environmentally friendly than conventional metal catalysts used in industry, they note, adding that it also displays the high enantioselectivity required by the pharmaceutical industry. “On top of these advantages, our newly developed organic catalyst system also promotes reactions using pyruvate that aren’t easily achievable using metal catalysts,” says Santanu Mondal, a PhD candidate in the chemistry and chemical bioengineering unit at Okinawa Institute of Science and Technology (OIST) Graduate University, Okinawa, Japan, and lead author of a study recently published in Organic Letters. “Organic catalysts, in particular, are set to revolutionize the industry and make chemistry more sustainable,” he stresses. The researchers use an acid and an amine mixture to force the pyruvate to act as an electron donor rather than its usual role as an electron receiver (Figure 1). Effectively mimicking how enzymes work, the amine binds to the pyruvate to make an intermediate molecule. The organic acid then covers up part of the intermediate molecule while leaving another part that can donate electrons free to react to form a new product. Currently, the organic catalyst system only works when reacting pyruvate with a specific class of organic molecule called cyclic imines. So, the researchers now are looking to develop a more-universal catalyst, i.e., one that can speed up reactions between pyruvate and a broad range of organic molecules. The challenge here is to try to make the electron-donating intermediate stage of pyruvate react with other functional groups such as aldehydes and ketones. However, different catalysts create different intermediates, all with different properties. For example, the enamine intermediate created by the researchers’ new reaction only reacts with cyclic imines. Their hypothesis, currently being investigated, is that creation of other intermediates such as an enolate, if possible, would achieve a broader pyruvate reactivity. In terms of cost, the researchers note that a palladium catalyst used in similar reactions is 25 times more expensive than their organic acid — which also is made from eco-friendly quinine. In addition, they believe scale-up of the process for industrial use definitely is possible. However, the researchers caution that the current amine-to-acid-catalyst loading ratio of 1:2 probably would need to be optimized for better results at a larger scale.

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Chemical Technology

Guyana-Suriname basin: Rise from obscurity to super potential

Article | August 2, 2022

Recent discoveries in the Guyana-Suriname basin attest to estimates of 10+ Bbbl of oil resources and more than 30 Tcf of gas.1 Like many oil & gas successes, this is a story that begins with early exploration success onshore, followed by a long period of exploration disappointment in coastal to shelf regions offshore, eventually culminating in deepwater success.

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Chemical Technology

The supply-chain inflation threat to petrochemicals demand

Article | July 20, 2022

Petrochemicals themselves remain in short supply. This is partly because of reduced feedstock from refineries, a consequence of the pandemic-related collapse in transportation fuels demand.Global petrochemical supply is still edging back to something like normal following the US winter storms in February, during which most US capacity was shut down. A point of discussion is whether containers will become available in the right places at the right prices to relieve tightness in the European polyethylene (PE) market, once US supply has normalised. The container issue is making it difficult to move PE and polypropylene (PP) cargoes from Asia to Europe.Market intelligence from the US-based ICIS CDI team indicates that enough container freight space will be available to resume significant shipments of US PE to Europe, albeit at high prices. It will be several more weeks before domestic pipelines have been refilled, enabling US producers to refocus on exports, added CDI.

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Chemical Management

Global polyolefins for the rest of 2021: supply to lengthen as demand muddle continues

Article | May 2, 2021

SOMEHOW, despite the still very serious container freight shortages that have limited imports, buying sentiment seems to have weakened in the European polyolefins market, according to my outstanding ICIS colleague, Linda Naylor.

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Spotlight

FourQuest Energy

With our industry-leading fleet of equipment, experienced personnel and engineering capabilities we provide our clients the most efficient turnaround and maintenance programs, nitrogen when you need it, proven specialty chemicals, and a full range of pre-commissioning and commissioning services. You can trust us for all your industrial cleaning needs at oil and gas, refinery, petrochemical and many other industrial facilities across North America.

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Chemical Management

Olin - Winchester Acquires White Flyer Targets Business

prnewswire | October 03, 2023

Olin Corporation announced that it has completed the previously announced acquisition of White Flyer Targets, North America's preeminent leader in recreational trap, skeet, and sporting clay targets. White Flyer will be combined with the Winchester Ammunition business. The acquisition includes White Flyer's five state of the art manufacturing facilities in Coal Township, Pennsylvania; Dalton, Georgia; Webb City, Missouri; Knox, Indiana; and, San Bernardino, California and includes White Flyer's recently announced ECO FLYER® target product line. "We welcome our new White Flyer teammates," noted Brett Flaugher, president of Winchester Ammunition. "Together, we can enhance the continued growth of trap, skeet, sporting clays, and other shotgun sports. These two leading brands are renowned for unmatched quality and now offer increased value to our customers through comprehensive ammunition and clay target solutions for the thousands of shooting ranges across America." Olin funded the transaction with cash on hand and anticipates that the transaction will be immediately accretive to Olin's shareholders. OLIN COMPANY DESCRIPTION Olin Corporation is a leading vertically-integrated global manufacturer and distributor of chemical products and a leading U.S. manufacturer of ammunition. The chemical products produced include chlorine and caustic soda, vinyls, epoxies, chlorinated organics, bleach, hydrogen, and hydrochloric acid. Winchester's principal manufacturing facilities produce and distribute sporting ammunition, law enforcement ammunition, reloading components, small caliber military ammunition and components, industrial cartridges, and clay targets.

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Chemical Management

908 Devices Enters Initial Production Phase of US Department of Defense Aerosol and Vapor Chemical Agent Detector Program

businesswire | September 28, 2023

908 Devices Inc. a pioneer of purpose-built handheld and desktop devices for chemical and biochemical analysis, announces that it has entered the initial production phase of the Aerosol and Vapor Chemical Agent Detector (AVCAD) program. The company and its partner on the project, Smiths Detection, will initially produce 122 systems in this next phase. The systems, which have been in development and testing since 2019, are a next generation chemical detector, designed to detect, identify, alarm and report the presence of traditional and advanced threat vapors and aerosols. Using a wireless remote alarm capability, the AVCAD, which can be mounted or portable, will support missions for the U.S. Army, Navy, Coast Guard, and Marine Corps. To ensure the highest level of detection and to meet the key deployment needs of the U.S. Department of Defense, the AVCAD features the company’s High Pressure Mass Spectrometry (HPMS) technology. Mass spectrometry is considered to be the gold standard of analytical lab techniques. 908 Devices’ proprietary HPMS technology leverages micro scale geometries and high frequency electronics to enable an efficient regime of vacuum operation for a significant reduction in device size and power consumption compared to conventional lab instruments. “908 Devices is pleased to continue working with the U.S. Department of Defense and our partner, Smiths Detection, on this enterprise, multi-year program,” said Kevin J. Knopp, CEO and Co-founder of 908 Devices. “Being selected for this limited production phase validates our technology as a new standard for chemical detection and we are truly honored to have a role in protecting our U.S. military.” About 908 Devices 908 Devices is revolutionizing chemical and biochemical analysis with its simple handheld and desktop devices, addressing critical-to-life applications. The Company’s devices are used at the point-of-need to interrogate unknown and invisible materials and provide quick, actionable answers to directly address some of the most critical problems in life sciences research, bioprocessing, pharma/biopharma, forensics and adjacent markets. The Company is headquartered in the heart of Boston, where it designs and manufactures innovative products that bring together the power of mass spectrometry, microfluidic sampling and separations, software automation, and machine learning.

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Chemical Management

Actylis Launches a New cGMP WFI Generation, Storage, and Distribution System with Additional ISO Class 7 Manufacturing Space

businesswire | September 26, 2023

Actylis, a leading global manufacturer of critical raw materials and performance ingredients for the life sciences and specialty chemicals markets, today announced the launch of Water for Injection (WFI) and additional ISO Class 7 manufacturing space at its Baie d’Urfé site in Montreal, Canada. Used for the preparation of media, buffers, and other aqueous solutions, Actylis’ WFI meets monographs for pharmacopoeias worldwide, and can be provided in both custom and standard packaging configurations. Gilles Cottier, CEO at Actylis, said: “Today we are delighted to announce the opening of this new WFI system at our Baie d’Urfé site. Investment in this new WFI generation, storage, and distribution system reflects our ongoing commitment to support our customers, and to continuously develop our range of products and services. The new system positions us to be a preferred outsource partner for our customers’ buffer solutions. We understand that capacity is often a pinch-point for our customers, and we are delighted to be able to propose this option to them.” Damien O’Rourke, SVP Manufacturing Operations at Actylis added: “Our new WFI system, redundant with our Limerick, Ireland WFI capabilities, incorporates the latest advancements in water purification technology, adhering to Good Manufacturing Practices (cGMP) that guarantees the production of WFI that meets or exceeds the most rigorous quality standards. In addition to the services this enables for our customers, the investment provides Actylis and our customers with a robust multi-site business continuity plan to ensure dependable supply.” Jean-Francois Raymond, Site Director, elaborated on some of the specifics of the system: “We are excited to have this new system here at Baie d’Urfé come on stream. The WFI system is fully qualified with all supporting validation documents, and is capable of generating and maintaining water as per required USP and PhEur/BP specifications of Water for Injection.” The new system’s strategic location in Montreal positions it as a pivotal hub for biopharmaceutical companies across North America and beyond. Its proximity to major transportation networks ensures timely distribution of WFI to manufacturers, enabling them to streamline their production processes and meet growing market demands. About Actylis Actylis is a leading global manufacturer and supplier of differentiated specialty ingredients to life sciences and specialty chemicals end markets. With business operations in ten countries, Actylis manufactures and supplies over 4,500 chemical compounds used principally by the pharmaceutical, biopharmaceutical, nutritional, agricultural and specialty chemical industries. Building on a series of strategic acquisitions, Actylis has integrated their manufacturing, R&D, quality, and sourcing capabilities to create a worldwide supplier of critical raw materials that includes a robust manufacturing footprint. Its global operations include a significant presence on the ground in North America, Europe, India, and China. Actylis is well positioned to innovate new solutions, ensure quality, and customize products to meet customers’ specific needs. Its expanded capabilities and decades of global sourcing expertise are especially valuable now that supply chain management is a critical strategic issue for companies worldwide.

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Chemical Management

Olin - Winchester Acquires White Flyer Targets Business

prnewswire | October 03, 2023

Olin Corporation announced that it has completed the previously announced acquisition of White Flyer Targets, North America's preeminent leader in recreational trap, skeet, and sporting clay targets. White Flyer will be combined with the Winchester Ammunition business. The acquisition includes White Flyer's five state of the art manufacturing facilities in Coal Township, Pennsylvania; Dalton, Georgia; Webb City, Missouri; Knox, Indiana; and, San Bernardino, California and includes White Flyer's recently announced ECO FLYER® target product line. "We welcome our new White Flyer teammates," noted Brett Flaugher, president of Winchester Ammunition. "Together, we can enhance the continued growth of trap, skeet, sporting clays, and other shotgun sports. These two leading brands are renowned for unmatched quality and now offer increased value to our customers through comprehensive ammunition and clay target solutions for the thousands of shooting ranges across America." Olin funded the transaction with cash on hand and anticipates that the transaction will be immediately accretive to Olin's shareholders. OLIN COMPANY DESCRIPTION Olin Corporation is a leading vertically-integrated global manufacturer and distributor of chemical products and a leading U.S. manufacturer of ammunition. The chemical products produced include chlorine and caustic soda, vinyls, epoxies, chlorinated organics, bleach, hydrogen, and hydrochloric acid. Winchester's principal manufacturing facilities produce and distribute sporting ammunition, law enforcement ammunition, reloading components, small caliber military ammunition and components, industrial cartridges, and clay targets.

Read More

Chemical Management

908 Devices Enters Initial Production Phase of US Department of Defense Aerosol and Vapor Chemical Agent Detector Program

businesswire | September 28, 2023

908 Devices Inc. a pioneer of purpose-built handheld and desktop devices for chemical and biochemical analysis, announces that it has entered the initial production phase of the Aerosol and Vapor Chemical Agent Detector (AVCAD) program. The company and its partner on the project, Smiths Detection, will initially produce 122 systems in this next phase. The systems, which have been in development and testing since 2019, are a next generation chemical detector, designed to detect, identify, alarm and report the presence of traditional and advanced threat vapors and aerosols. Using a wireless remote alarm capability, the AVCAD, which can be mounted or portable, will support missions for the U.S. Army, Navy, Coast Guard, and Marine Corps. To ensure the highest level of detection and to meet the key deployment needs of the U.S. Department of Defense, the AVCAD features the company’s High Pressure Mass Spectrometry (HPMS) technology. Mass spectrometry is considered to be the gold standard of analytical lab techniques. 908 Devices’ proprietary HPMS technology leverages micro scale geometries and high frequency electronics to enable an efficient regime of vacuum operation for a significant reduction in device size and power consumption compared to conventional lab instruments. “908 Devices is pleased to continue working with the U.S. Department of Defense and our partner, Smiths Detection, on this enterprise, multi-year program,” said Kevin J. Knopp, CEO and Co-founder of 908 Devices. “Being selected for this limited production phase validates our technology as a new standard for chemical detection and we are truly honored to have a role in protecting our U.S. military.” About 908 Devices 908 Devices is revolutionizing chemical and biochemical analysis with its simple handheld and desktop devices, addressing critical-to-life applications. The Company’s devices are used at the point-of-need to interrogate unknown and invisible materials and provide quick, actionable answers to directly address some of the most critical problems in life sciences research, bioprocessing, pharma/biopharma, forensics and adjacent markets. The Company is headquartered in the heart of Boston, where it designs and manufactures innovative products that bring together the power of mass spectrometry, microfluidic sampling and separations, software automation, and machine learning.

Read More

Chemical Management

Actylis Launches a New cGMP WFI Generation, Storage, and Distribution System with Additional ISO Class 7 Manufacturing Space

businesswire | September 26, 2023

Actylis, a leading global manufacturer of critical raw materials and performance ingredients for the life sciences and specialty chemicals markets, today announced the launch of Water for Injection (WFI) and additional ISO Class 7 manufacturing space at its Baie d’Urfé site in Montreal, Canada. Used for the preparation of media, buffers, and other aqueous solutions, Actylis’ WFI meets monographs for pharmacopoeias worldwide, and can be provided in both custom and standard packaging configurations. Gilles Cottier, CEO at Actylis, said: “Today we are delighted to announce the opening of this new WFI system at our Baie d’Urfé site. Investment in this new WFI generation, storage, and distribution system reflects our ongoing commitment to support our customers, and to continuously develop our range of products and services. The new system positions us to be a preferred outsource partner for our customers’ buffer solutions. We understand that capacity is often a pinch-point for our customers, and we are delighted to be able to propose this option to them.” Damien O’Rourke, SVP Manufacturing Operations at Actylis added: “Our new WFI system, redundant with our Limerick, Ireland WFI capabilities, incorporates the latest advancements in water purification technology, adhering to Good Manufacturing Practices (cGMP) that guarantees the production of WFI that meets or exceeds the most rigorous quality standards. In addition to the services this enables for our customers, the investment provides Actylis and our customers with a robust multi-site business continuity plan to ensure dependable supply.” Jean-Francois Raymond, Site Director, elaborated on some of the specifics of the system: “We are excited to have this new system here at Baie d’Urfé come on stream. The WFI system is fully qualified with all supporting validation documents, and is capable of generating and maintaining water as per required USP and PhEur/BP specifications of Water for Injection.” The new system’s strategic location in Montreal positions it as a pivotal hub for biopharmaceutical companies across North America and beyond. Its proximity to major transportation networks ensures timely distribution of WFI to manufacturers, enabling them to streamline their production processes and meet growing market demands. About Actylis Actylis is a leading global manufacturer and supplier of differentiated specialty ingredients to life sciences and specialty chemicals end markets. With business operations in ten countries, Actylis manufactures and supplies over 4,500 chemical compounds used principally by the pharmaceutical, biopharmaceutical, nutritional, agricultural and specialty chemical industries. Building on a series of strategic acquisitions, Actylis has integrated their manufacturing, R&D, quality, and sourcing capabilities to create a worldwide supplier of critical raw materials that includes a robust manufacturing footprint. Its global operations include a significant presence on the ground in North America, Europe, India, and China. Actylis is well positioned to innovate new solutions, ensure quality, and customize products to meet customers’ specific needs. Its expanded capabilities and decades of global sourcing expertise are especially valuable now that supply chain management is a critical strategic issue for companies worldwide.

Read More

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