Identifying chemical health hazards from Safety Data Sheets (SDSs)

WALTER INGLES | January 14, 2019 | 181 views

Safety Data Sheets are an essential part of managing the risks created by hazardous chemicals. Apart from being legally required onsite (in work and storage areas where chemicals are kept), SDSs are key to identifying and understanding the way chemicals could impact the health of your workers or other site personnel. This blog is a step-by-step approach to using an SDS as the basis for identifying chemical health hazards and assessing the exposure levels that could cause injuries, death, or long term illness.

Spotlight

ELANTAS PDG, Inc.

ELANTAS PDG, Inc. is the global leader in liquid electrical insulation products, including magnet wire enamel, insulating resins, potting compounds, conformal coatings, insulating films and a wide range of specialty resin systems and adhesives. ISO 9001, TS 16949. A Heritage of Innovation since 1919.

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Chemical Technology

The supply-chain inflation threat to petrochemicals demand

Article | July 20, 2022

Petrochemicals themselves remain in short supply. This is partly because of reduced feedstock from refineries, a consequence of the pandemic-related collapse in transportation fuels demand.Global petrochemical supply is still edging back to something like normal following the US winter storms in February, during which most US capacity was shut down. A point of discussion is whether containers will become available in the right places at the right prices to relieve tightness in the European polyethylene (PE) market, once US supply has normalised. The container issue is making it difficult to move PE and polypropylene (PP) cargoes from Asia to Europe.Market intelligence from the US-based ICIS CDI team indicates that enough container freight space will be available to resume significant shipments of US PE to Europe, albeit at high prices. It will be several more weeks before domestic pipelines have been refilled, enabling US producers to refocus on exports, added CDI.

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Chemical Technology

Boom in petrochemicals demand guaranteed but we must grow sustainably

Article | August 8, 2022

ONE OF THE GREATEST achievements of the last 30 years has been the fall in the number of people living in extreme poverty.In 1999, 1.9bn of the world’s population were living on less than $1.90, the Word Bank’s definition of extreme poverty. Despite setbacks caused by the pandemic, this had fallen to 698m by October 2020. Income levels alone are not enough to escape the life-threatening agony of extreme poverty. There is no point in having money if the essential goods and services to spend your money on are not available. Critical to poverty alleviation has been sufficient supply of all the things that people in the rich world take for granted. The raw materials to make the vast majority of manufactured goods include petrochemicals and polymers. Nearly all the major manufacturing chains would not have been able to function without petrochemicals. Think of medical equipment, syringes, blood bags, hospital gowns, face masks, pill bottles and medicine blister packs. None of the above could have been produced without petrochemicals. As people emerged out of extreme poverty and as economies became wealthier, modern-day medical services became more widely available.

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Chemical Management

Application of Chromatography in Various Industries is Changing the Game!

Article | July 14, 2022

Used to separate and analyze compounds into their various components— chromatography plays a crucial part not just in the food industry but in the realms of drug testing, forensics, and even quality control in our favourite alcoholic drinks as well. Advanced Chromatography is an analytical technique introduced to the world by chromatography instrument companies to separate and analyze individual chemicals from complex compounds. Recent developments in the biotechnology and pharma industries have created a significant surge in the chromatography market. Read on to find out five fascinating facts about the day-to-day applications of chromatography in various industries and why businesses are looking to invest more in OEM chromatography manufacturing. Why are Industry-Decision Makers Adapting to Chromatography? Liquid Chromatography; A Popular Choice in Drug Testing Today, a lot of drug tests use liquid chromatography-mass spectrometry because it is easy to use, widely available, and gives quick results. LC and LC-MS can be done in almost any testing facility, which is different from other methods. It can be run by people with little training, so a testing facility can hire mostly technicians instead of highly trained scientists, who are harder to find. LC-MS is also very accurate, which means that there are fewer false positives. With liquid chromatography, you can get results in about 10 to 30 minutes, which is very fast. This technology is used by many drug testing labs across the country. It is widely used and trusted for testing drug samples and many other things. Businesses associated with the sports industry are leveraging chromatography to effectively and accurately test athletes for doping or performance-enhancing drugs. Use of HPCL in Pharmaceutical Industries Chromatography is used in the medical and pharmaceutical industries to create vaccines. In addition, chromatography can determine which antibodies best neutralize viruses and diseases. Mapp Biopharmaceutical, Inc. used the chromatography technique to develop the experimental immunization Zmapp to counteract the deadly Ebola virus. And it is still being used today to fight the coronavirus. The pharmaceutical industry has gained enormous success by exclusively using HPLC to obtain precise results during drug trials. The results can be used to analyze finished drug products and their ingredients quantitatively and qualitatively during manufacturing. The Detector in Forensic Science Chromatography methods are a well-established, powerful suite of methodologies in forensic science, from drug busts, murders, and robberies, to the identification of a plethora of chemical compounds that may be present in samples from terrorist incidents. Forensics use gas chromatography to help solve crimes. It helps analyze blood and clothing samples, allowing forensic scientists to investigate who and what was present at a crime scene. In particular instances, chromatography can even help forensic scientists pinpoint the exact whereabouts of the alleged perpetrator and victim before the crime happened. It’s an error-free process. Therefore, it is incredibly helpful in court. Additionally, chromatography is extremely handy in arson investigations. Most fires have a virtual cocktail of different substances. Every compound and substance differs in size and weight. Chromatography helps break down these varying compounds and substances to help determine what exactly started the fire. Liquid Chromatography in Food Industry Liquid chromatography plays a vital role in the food industry nowadays. It absolves and permits the selective removal of a wide variety of flavor and non-flavor-active food ingredients. The USDA, along with other countries, has prioritized rigorous testing of processed meat's contents. For example, in 2013, it was found that horsemeat was being sold as beef without anyone noticing. As a result, the food industry decided to change its analytical techniques. Chromatography quickly became the best way to find out what was in processed meats. High-Performance Liquid Chromatography and mass spectrometry were used to ensure that meat labeled beef was actually beef. In addition, it could tell if horse meat was mixed in with the beef, which helped keep people safe. Bio-Rad Fast Acid Analysis Column in Beverage Testing Not just food, many beverage manufacturers also use chromatography to ensure that each bottle of their product is the same. But, again, consistent taste is the main priority. And knowing the exact content of each bottle is the most proactive way to measure things. The Bio-Rad fast acid analysis column has been successfully used by many companies to quantitatively determine vitamin C in juices, fresh drinks, and powdered drinks. Chromatography Market is Opening New Dimensions in Various Businesses Undoubtedly, technological advancement has created a vigorous need for chromatography devices. According to Verified Market Research, growing at a CAGR of 3.4% from 2020 to 2027, the chromatography market is projected to reach USD 4.73 billion by 2027. The chromatography instrumentation market is currently witnessing huge advancements in the design of columns. This is raising the demand for development of better analytical reagents and resins. Increasing collaborations among the existing players, specifically in the Asian market is another propelling factor for this market. Additionally, emergence of green chromatography, increasing usage of chromatography instruments for monoclonal antibody purification, and usage of nanomaterial in chromatography are also fuelling the growth of this market. Plus, increased government funding in research and development activities is further driving the market growth. With various pharmaceutical and biotechnology companies, chemical, food and beverage, and other industries contributing to its market growth, one thing is for sure— the increase in the chromatography system market is here to stay.

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Chemical Management

Global polyethylene demand boom likely, increasing the sustainability challenge

Article | June 15, 2021

IT FEELS LIKE several lifetimes ago. If you recall, way back in November-December 2019 Asian variable cost integrated naphtha-based polyethylene (PE) margins turned negative because of the increase in US capacity. Then in January the following year, deep Asian and Middle East operating rate cuts returned some order to the market. Then, bang, as we all know, the pandemic arrived and turned everything on its head. The pandemic has, in my view, accentuated trends that were already well underway. I believe this means that the supply-driven downturn that started in late 2019 will not return.Long before coronavirus upended everyone’s lives, PE demand was becoming increasingly divorced from GDP growth because of the shifting nature of end-use demand. Booming internet sales was, I believe, a major factor behind the split between the growth of the overall economies in the developed world plus China and PE demand.The average product bought online is dropped 17 times because of the large number of people involved in the logistics chain, according to Forbes. This had led to a surge in demand for protective packaging made not from PE and other polymers such as polypropylene, expandable polystyrene and PET films (I will look at their demand growth prospects in later posts).Despite sustainability pressures, the scale of demand for stuff bought online translated to a lot more consumption of virgin polymers.

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Spotlight

ELANTAS PDG, Inc.

ELANTAS PDG, Inc. is the global leader in liquid electrical insulation products, including magnet wire enamel, insulating resins, potting compounds, conformal coatings, insulating films and a wide range of specialty resin systems and adhesives. ISO 9001, TS 16949. A Heritage of Innovation since 1919.

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Chemical Management

908 Devices Enters Initial Production Phase of US Department of Defense Aerosol and Vapor Chemical Agent Detector Program

businesswire | September 28, 2023

908 Devices Inc. a pioneer of purpose-built handheld and desktop devices for chemical and biochemical analysis, announces that it has entered the initial production phase of the Aerosol and Vapor Chemical Agent Detector (AVCAD) program. The company and its partner on the project, Smiths Detection, will initially produce 122 systems in this next phase. The systems, which have been in development and testing since 2019, are a next generation chemical detector, designed to detect, identify, alarm and report the presence of traditional and advanced threat vapors and aerosols. Using a wireless remote alarm capability, the AVCAD, which can be mounted or portable, will support missions for the U.S. Army, Navy, Coast Guard, and Marine Corps. To ensure the highest level of detection and to meet the key deployment needs of the U.S. Department of Defense, the AVCAD features the company’s High Pressure Mass Spectrometry (HPMS) technology. Mass spectrometry is considered to be the gold standard of analytical lab techniques. 908 Devices’ proprietary HPMS technology leverages micro scale geometries and high frequency electronics to enable an efficient regime of vacuum operation for a significant reduction in device size and power consumption compared to conventional lab instruments. “908 Devices is pleased to continue working with the U.S. Department of Defense and our partner, Smiths Detection, on this enterprise, multi-year program,” said Kevin J. Knopp, CEO and Co-founder of 908 Devices. “Being selected for this limited production phase validates our technology as a new standard for chemical detection and we are truly honored to have a role in protecting our U.S. military.” About 908 Devices 908 Devices is revolutionizing chemical and biochemical analysis with its simple handheld and desktop devices, addressing critical-to-life applications. The Company’s devices are used at the point-of-need to interrogate unknown and invisible materials and provide quick, actionable answers to directly address some of the most critical problems in life sciences research, bioprocessing, pharma/biopharma, forensics and adjacent markets. The Company is headquartered in the heart of Boston, where it designs and manufactures innovative products that bring together the power of mass spectrometry, microfluidic sampling and separations, software automation, and machine learning.

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Chemical Management

Actylis Launches a New cGMP WFI Generation, Storage, and Distribution System with Additional ISO Class 7 Manufacturing Space

businesswire | September 26, 2023

Actylis, a leading global manufacturer of critical raw materials and performance ingredients for the life sciences and specialty chemicals markets, today announced the launch of Water for Injection (WFI) and additional ISO Class 7 manufacturing space at its Baie d’Urfé site in Montreal, Canada. Used for the preparation of media, buffers, and other aqueous solutions, Actylis’ WFI meets monographs for pharmacopoeias worldwide, and can be provided in both custom and standard packaging configurations. Gilles Cottier, CEO at Actylis, said: “Today we are delighted to announce the opening of this new WFI system at our Baie d’Urfé site. Investment in this new WFI generation, storage, and distribution system reflects our ongoing commitment to support our customers, and to continuously develop our range of products and services. The new system positions us to be a preferred outsource partner for our customers’ buffer solutions. We understand that capacity is often a pinch-point for our customers, and we are delighted to be able to propose this option to them.” Damien O’Rourke, SVP Manufacturing Operations at Actylis added: “Our new WFI system, redundant with our Limerick, Ireland WFI capabilities, incorporates the latest advancements in water purification technology, adhering to Good Manufacturing Practices (cGMP) that guarantees the production of WFI that meets or exceeds the most rigorous quality standards. In addition to the services this enables for our customers, the investment provides Actylis and our customers with a robust multi-site business continuity plan to ensure dependable supply.” Jean-Francois Raymond, Site Director, elaborated on some of the specifics of the system: “We are excited to have this new system here at Baie d’Urfé come on stream. The WFI system is fully qualified with all supporting validation documents, and is capable of generating and maintaining water as per required USP and PhEur/BP specifications of Water for Injection.” The new system’s strategic location in Montreal positions it as a pivotal hub for biopharmaceutical companies across North America and beyond. Its proximity to major transportation networks ensures timely distribution of WFI to manufacturers, enabling them to streamline their production processes and meet growing market demands. About Actylis Actylis is a leading global manufacturer and supplier of differentiated specialty ingredients to life sciences and specialty chemicals end markets. With business operations in ten countries, Actylis manufactures and supplies over 4,500 chemical compounds used principally by the pharmaceutical, biopharmaceutical, nutritional, agricultural and specialty chemical industries. Building on a series of strategic acquisitions, Actylis has integrated their manufacturing, R&D, quality, and sourcing capabilities to create a worldwide supplier of critical raw materials that includes a robust manufacturing footprint. Its global operations include a significant presence on the ground in North America, Europe, India, and China. Actylis is well positioned to innovate new solutions, ensure quality, and customize products to meet customers’ specific needs. Its expanded capabilities and decades of global sourcing expertise are especially valuable now that supply chain management is a critical strategic issue for companies worldwide.

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Chemical Management

Danimer Scientific and Chevron Phillips Chemical Expand Collaboration to Include Application Development for Rinnovo™ Polymers

businesswire | September 21, 2023

Danimer Scientific, Inc. a leading next-generation bioplastics company focused on the development and production of biodegradable materials, today announced it is expanding its collaboration with Chevron Phillips Chemical (“CPChem”) to explore development and commercialization of cast extrusion films, blown extrusion films, injection molded parts and rotational molded parts using Rinnovo™ polymers produced in a loop slurry reactor process. Rinnovo™ is a type of polyhydroxyalkanoate (“PHA”) synthesized from lactones produced using Danimer’s proprietary Novo22™ catalyst technology, which can be used in the production of biodegradable alternatives to traditional plastics. The collaboration expands on Danimer and CPChem’s previously announced agreement, in which Danimer is evaluating the use of CPChem’s loop slurry reactor design to develop a continuous reactor system in the manufacturing process for Rinnovo™. Stephen E. Croskrey, chief executive officer of Danimer, said, “Our business relationship with CPChem continues to yield results, and we’re excited for the further opportunities that lie ahead. CPChem’s Research and Technology lab in Bartlesville, Oklahoma, is a premier facility staffed with world-class talent that we believe will accelerate the path toward adoption of Rinnovo™ materials in high-volume applications that will assist in lowering the cost to serve key markets.” Opened in 1950 by Phillips 66, CPChem’s Bartlesville facility contains first-class research equipment allowing for rapid testing of products across various processing conditions. Additionally, the facility’s testing and analytical capabilities provide a more rapid feedback loop, accelerating the development and optimization of resin formulations. “We continue to be excited about the potential of our MarTECH® process technology and related collaborations to advance Danimer’s Rinnovo™, another CPChem initiative that can help accelerate change for a more sustainable future,” said Venki Chandrashekar, CPChem vice president of research and technology. About Danimer Scientific Danimer is a pioneer in creating more sustainable, more natural ways to make plastic products. For more than a decade, its renewable and sustainable biopolymers have helped create plastic products that are biodegradable and compostable and return to nature instead of polluting our lands and waters. Danimer’s technology can be found in a vast array of plastic end products that people use every day. Applications for its biopolymers include additives, aqueous coatings, fibers, filaments, films and injection-molded articles, among others. Danimer holds more than 430 granted patents and pending patent applications in more than 20 countries for a range of manufacturing processes and biopolymer formulations.

Read More

Chemical Management

908 Devices Enters Initial Production Phase of US Department of Defense Aerosol and Vapor Chemical Agent Detector Program

businesswire | September 28, 2023

908 Devices Inc. a pioneer of purpose-built handheld and desktop devices for chemical and biochemical analysis, announces that it has entered the initial production phase of the Aerosol and Vapor Chemical Agent Detector (AVCAD) program. The company and its partner on the project, Smiths Detection, will initially produce 122 systems in this next phase. The systems, which have been in development and testing since 2019, are a next generation chemical detector, designed to detect, identify, alarm and report the presence of traditional and advanced threat vapors and aerosols. Using a wireless remote alarm capability, the AVCAD, which can be mounted or portable, will support missions for the U.S. Army, Navy, Coast Guard, and Marine Corps. To ensure the highest level of detection and to meet the key deployment needs of the U.S. Department of Defense, the AVCAD features the company’s High Pressure Mass Spectrometry (HPMS) technology. Mass spectrometry is considered to be the gold standard of analytical lab techniques. 908 Devices’ proprietary HPMS technology leverages micro scale geometries and high frequency electronics to enable an efficient regime of vacuum operation for a significant reduction in device size and power consumption compared to conventional lab instruments. “908 Devices is pleased to continue working with the U.S. Department of Defense and our partner, Smiths Detection, on this enterprise, multi-year program,” said Kevin J. Knopp, CEO and Co-founder of 908 Devices. “Being selected for this limited production phase validates our technology as a new standard for chemical detection and we are truly honored to have a role in protecting our U.S. military.” About 908 Devices 908 Devices is revolutionizing chemical and biochemical analysis with its simple handheld and desktop devices, addressing critical-to-life applications. The Company’s devices are used at the point-of-need to interrogate unknown and invisible materials and provide quick, actionable answers to directly address some of the most critical problems in life sciences research, bioprocessing, pharma/biopharma, forensics and adjacent markets. The Company is headquartered in the heart of Boston, where it designs and manufactures innovative products that bring together the power of mass spectrometry, microfluidic sampling and separations, software automation, and machine learning.

Read More

Chemical Management

Actylis Launches a New cGMP WFI Generation, Storage, and Distribution System with Additional ISO Class 7 Manufacturing Space

businesswire | September 26, 2023

Actylis, a leading global manufacturer of critical raw materials and performance ingredients for the life sciences and specialty chemicals markets, today announced the launch of Water for Injection (WFI) and additional ISO Class 7 manufacturing space at its Baie d’Urfé site in Montreal, Canada. Used for the preparation of media, buffers, and other aqueous solutions, Actylis’ WFI meets monographs for pharmacopoeias worldwide, and can be provided in both custom and standard packaging configurations. Gilles Cottier, CEO at Actylis, said: “Today we are delighted to announce the opening of this new WFI system at our Baie d’Urfé site. Investment in this new WFI generation, storage, and distribution system reflects our ongoing commitment to support our customers, and to continuously develop our range of products and services. The new system positions us to be a preferred outsource partner for our customers’ buffer solutions. We understand that capacity is often a pinch-point for our customers, and we are delighted to be able to propose this option to them.” Damien O’Rourke, SVP Manufacturing Operations at Actylis added: “Our new WFI system, redundant with our Limerick, Ireland WFI capabilities, incorporates the latest advancements in water purification technology, adhering to Good Manufacturing Practices (cGMP) that guarantees the production of WFI that meets or exceeds the most rigorous quality standards. In addition to the services this enables for our customers, the investment provides Actylis and our customers with a robust multi-site business continuity plan to ensure dependable supply.” Jean-Francois Raymond, Site Director, elaborated on some of the specifics of the system: “We are excited to have this new system here at Baie d’Urfé come on stream. The WFI system is fully qualified with all supporting validation documents, and is capable of generating and maintaining water as per required USP and PhEur/BP specifications of Water for Injection.” The new system’s strategic location in Montreal positions it as a pivotal hub for biopharmaceutical companies across North America and beyond. Its proximity to major transportation networks ensures timely distribution of WFI to manufacturers, enabling them to streamline their production processes and meet growing market demands. About Actylis Actylis is a leading global manufacturer and supplier of differentiated specialty ingredients to life sciences and specialty chemicals end markets. With business operations in ten countries, Actylis manufactures and supplies over 4,500 chemical compounds used principally by the pharmaceutical, biopharmaceutical, nutritional, agricultural and specialty chemical industries. Building on a series of strategic acquisitions, Actylis has integrated their manufacturing, R&D, quality, and sourcing capabilities to create a worldwide supplier of critical raw materials that includes a robust manufacturing footprint. Its global operations include a significant presence on the ground in North America, Europe, India, and China. Actylis is well positioned to innovate new solutions, ensure quality, and customize products to meet customers’ specific needs. Its expanded capabilities and decades of global sourcing expertise are especially valuable now that supply chain management is a critical strategic issue for companies worldwide.

Read More

Chemical Management

Danimer Scientific and Chevron Phillips Chemical Expand Collaboration to Include Application Development for Rinnovo™ Polymers

businesswire | September 21, 2023

Danimer Scientific, Inc. a leading next-generation bioplastics company focused on the development and production of biodegradable materials, today announced it is expanding its collaboration with Chevron Phillips Chemical (“CPChem”) to explore development and commercialization of cast extrusion films, blown extrusion films, injection molded parts and rotational molded parts using Rinnovo™ polymers produced in a loop slurry reactor process. Rinnovo™ is a type of polyhydroxyalkanoate (“PHA”) synthesized from lactones produced using Danimer’s proprietary Novo22™ catalyst technology, which can be used in the production of biodegradable alternatives to traditional plastics. The collaboration expands on Danimer and CPChem’s previously announced agreement, in which Danimer is evaluating the use of CPChem’s loop slurry reactor design to develop a continuous reactor system in the manufacturing process for Rinnovo™. Stephen E. Croskrey, chief executive officer of Danimer, said, “Our business relationship with CPChem continues to yield results, and we’re excited for the further opportunities that lie ahead. CPChem’s Research and Technology lab in Bartlesville, Oklahoma, is a premier facility staffed with world-class talent that we believe will accelerate the path toward adoption of Rinnovo™ materials in high-volume applications that will assist in lowering the cost to serve key markets.” Opened in 1950 by Phillips 66, CPChem’s Bartlesville facility contains first-class research equipment allowing for rapid testing of products across various processing conditions. Additionally, the facility’s testing and analytical capabilities provide a more rapid feedback loop, accelerating the development and optimization of resin formulations. “We continue to be excited about the potential of our MarTECH® process technology and related collaborations to advance Danimer’s Rinnovo™, another CPChem initiative that can help accelerate change for a more sustainable future,” said Venki Chandrashekar, CPChem vice president of research and technology. About Danimer Scientific Danimer is a pioneer in creating more sustainable, more natural ways to make plastic products. For more than a decade, its renewable and sustainable biopolymers have helped create plastic products that are biodegradable and compostable and return to nature instead of polluting our lands and waters. Danimer’s technology can be found in a vast array of plastic end products that people use every day. Applications for its biopolymers include additives, aqueous coatings, fibers, filaments, films and injection-molded articles, among others. Danimer holds more than 430 granted patents and pending patent applications in more than 20 countries for a range of manufacturing processes and biopolymer formulations.

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