Green Chemistry and Contract Synthesis – a Contradiction?

June 17, 2021 | 4 views

The topic of green chemistry is now also a challenge for contract synthesis suppliers. This is because more and more manufacturers of shampoos, detergents, paints, packaging and other consumer products are becoming increasingly concerned about the ecological footprint of their products.

The trend is being fueled by consumers, who are increasingly prepared to spend more money on products that are better for the environment. But the political environment is also exerting major pressure on companies.

Spotlight

Kinsy

Kinsy is an independent manufacturer of fine chemicals, located in Spain. The company was founded in 1991; it is family-owned and employs 70 people. The main activity of our company is contract development and synthesis of fine chemicals, mainly advanced pharmaceutical intermediates and APIs. As a result of its small size and efficient organization, our company has a fast, flexible and competitive response to customer’s enquiries, including.

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CHEMICAL TECHNOLOGY

Organic Catalyst Boasts Big Benefits

Article | June 6, 2022

An enzyme-mimicking catalyst opens a new route to important organic molecules such as glycolic acid and amino acids from pyruvate, report researchers in Japan. Moreover, the new catalyst is cheaper, more stable, safer and more environmentally friendly than conventional metal catalysts used in industry, they note, adding that it also displays the high enantioselectivity required by the pharmaceutical industry. “On top of these advantages, our newly developed organic catalyst system also promotes reactions using pyruvate that aren’t easily achievable using metal catalysts,” says Santanu Mondal, a PhD candidate in the chemistry and chemical bioengineering unit at Okinawa Institute of Science and Technology (OIST) Graduate University, Okinawa, Japan, and lead author of a study recently published in Organic Letters. “Organic catalysts, in particular, are set to revolutionize the industry and make chemistry more sustainable,” he stresses. The researchers use an acid and an amine mixture to force the pyruvate to act as an electron donor rather than its usual role as an electron receiver (Figure 1). Effectively mimicking how enzymes work, the amine binds to the pyruvate to make an intermediate molecule. The organic acid then covers up part of the intermediate molecule while leaving another part that can donate electrons free to react to form a new product. Currently, the organic catalyst system only works when reacting pyruvate with a specific class of organic molecule called cyclic imines. So, the researchers now are looking to develop a more-universal catalyst, i.e., one that can speed up reactions between pyruvate and a broad range of organic molecules. The challenge here is to try to make the electron-donating intermediate stage of pyruvate react with other functional groups such as aldehydes and ketones. However, different catalysts create different intermediates, all with different properties. For example, the enamine intermediate created by the researchers’ new reaction only reacts with cyclic imines. Their hypothesis, currently being investigated, is that creation of other intermediates such as an enolate, if possible, would achieve a broader pyruvate reactivity. In terms of cost, the researchers note that a palladium catalyst used in similar reactions is 25 times more expensive than their organic acid — which also is made from eco-friendly quinine. In addition, they believe scale-up of the process for industrial use definitely is possible. However, the researchers caution that the current amine-to-acid-catalyst loading ratio of 1:2 probably would need to be optimized for better results at a larger scale.

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CHEMICAL TECHNOLOGY

Transporting biological and chemical materials - what you need to know

Article | May 20, 2021

The landscape of biological and chemical logistics has changed rapidly - as have the regulatory frameworks around it. What has not necessarily kept pace is the end-user understanding of the nature of these logistical processes, their opportunities and their constraints. Twenty years ago, the transmission of biological and chemical materials was limited to a small range of organisations: usually national and international research companies, hospitals, major university departments, police and military departments with forensic responsibilities.

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CHEMICAL TECHNOLOGY

Setting record straight on testing harm in chemicals

Article | May 27, 2021

The modern world is built on chemicals, be it the medicines we use, or cleaning fluids, crop protection products, or the raw materials for everything from laptops and mobile phones to clothes and furniture. Across all, we have created an entire modern society with chemicals, and, as a result, constantly stretched the size of the world population we can feed, clothe and shelter. Yet, balancing all the gains from the modern chemistry around us against any negative environmental and human impact has been a rising concern, making for ever greater focus on testing and on risk assessment.

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Why chemical characterization is the best way to assess patient risk

Article | February 11, 2020

Everyone is very familiar with the phrase when buying a house: All that really matters are three things - location, location, and location. This same principle applies to extractables and leachables chemistry analysis – the three things that truly matter are identification, identification, and identification. The greatest growth in the past ten years in demonstrating the safety of medical devices and container closure systems for drugs has been using analytical chemistry to determine what chemicals can leach from the device and what the patient is exposed to during its intended use.

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Spotlight

Kinsy

Kinsy is an independent manufacturer of fine chemicals, located in Spain. The company was founded in 1991; it is family-owned and employs 70 people. The main activity of our company is contract development and synthesis of fine chemicals, mainly advanced pharmaceutical intermediates and APIs. As a result of its small size and efficient organization, our company has a fast, flexible and competitive response to customer’s enquiries, including.

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CHEMICAL MANAGEMENT

Oberon Fuels Joins International Trade Associations

Oberon Fuels | July 01, 2022

Oberon Fuels a maker of products that reduce greenhouse gas emissions of major energy sectors, has joined both the World Biogas Association and Liquid Gas Europe as Oberon continues to build upon its work in Europe and around the world. Oberon has developed a straightforward ‘here-now’ way to slash the CO2 emissions of the global Liquefied Petroleum Gas industry through the production of renewable dimethyl ether. Because rDME can be stored, transported and dispensed using existing LPG vehicles and equipment, it can be readily blended with fossil LPG to reduce carbon emissions by up to 60 percent. The intersection between rDME made from biogas and the LPG industry is a key reason for Oberon to join these trade associations. The EU consumes about 48 billion liters of LPG per year, of which an estimated 3.8 billion liters (1 billion gallons) are imported from Russia. Oberon Fuels can enable European countries to produce fuels from local renewable biomass with no indirect land use impacts while reducing the need to import foreign energy resources. To help meet the goals of the EU Green Deal, the EU market is ready for new approaches to decarbonizing a range of major uses including transport, heating and agriculture. Oberon’s interest in expanding into Europe and other global markets is intended to accelerate commercial adoption of rDME with near-term market trials leading to deployment of multiple commercial-scale production plants. Oberon already has strategic collaborations with leaders around the world including Suburban Propane (US) and South America-based Lipigas. Oberon executives were in Switzerland recently presenting at the International DME Association’s annual event, and company CEO Rebecca Boudreaux, Ph.D., spoke earlier today at the European Liquid Gas Congress event in Barcelona. About Oberon Fuels California-based Oberon Fuels is on a mission to decarbonize the fuel and energy sectors through the commercialization of renewable dimethyl ether. Oberon’s low or carbon-negative rDME can reduce the carbon intensity of propane by up to 60 percent when blended, offering potential reductions in global CO2 of 750 million metric tons per year. rDME’s characteristics also makes it a compelling means for transporting hydrogen for its myriad, fast-growing applications.

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CHEMICAL TECHNOLOGY

Twelve to Deploy World’s First Industrial-Scale Carbon Transformation Platform

Twelve | July 04, 2022

Twelve, the carbon transformation company, is announcing $130 million in Series B and additional funding to scale the engineering, manufacturing, and deployment of its industrial-scale carbon transformation technology for the creation of a wide range of products with a lower carbon footprint. Twelve’s carbon transformation technology converts captured CO2 into products historically made from fossil fuels. According to research from Columbia’s SIPA Center on Global Energy Policy, replacing fossil feedstocks in the production of chemicals, materials, and fuels with renewable carbon from point source or direct air capture could avoid nearly 10 percent of global greenhouse gas emissions. Twelve is currently transforming emissions into products for the automotive, household and apparel industries, as well as for government entities and global technology companies, by replacing petrochemicals and fossil-based transportation fuels with CO2Made® materials and carbon-neutral fuels like E-JetⓇ. “Companies and governments no longer need to rely on fossil fuels for the carbon that goes into everything from apparel and cleaning products to electronics and jet fuel. This fresh funding ensures we can reach industrial scale to help new and existing partners achieve rapid emissions-reduction.” Twelve Co-Founder and CEO Nicholas Flanders Twelve’s partners include Mercedes-Benz, Procter & Gamble, Shopify, the U.S. National Aeronautics and Space Administrationand the U.S. Air Force, all of which use Twelve’s breakthrough carbon transformation technology to reduce emissions and create CO2Made products. “As more companies and organizations adopt carbon-neutrality targets, they urgently need technologies like Twelve’s to rapidly green supply chains and corporate travel to reduce emissions at scale,” said Zachary Bogue, Managing Partner, DCVC. “Since leading Twelve’s seed round in 2018, we’ve only become more confident that their technology offers businesses a critical solution for not just offsetting emissions, but eliminating them.” The new funding follows Twelve’s first commercial products, a line of CO2Made sunglasses with sustainable fashion brand PANGAIA, and carbon-neutral sustainable aviation fuel (SAF), E-Jet. Twelve was recently recognized by Fast Company as the world’s #1 most innovative energy company of 2022 and as a BloombergNEF Pioneer in the Decarbonizing Aviation category. “Delivering low-carbon sustainable products consumers desire will require scaling innovative solutions such as Twelve’s carbon transformation technology.” said Todd Cline, Senior Director of Sustainability, for Procter & Gamble Fabric Care. “We’re glad to see Twelve given the opportunity to expand their opportunity to impact a broad variety of sustainable consumer products enabled by their technology.” “Twelve has the potential to disrupt petrochemical supply chains by creating a wide range of materials from carbon emissions instead of fossil fuels,” said Udo Gayer, Manager of New Business in Production Planning at Mercedes-Benz Cars. “The potential impact of their technology is immense, and I’m glad to see them receive the funding to continue scaling their technology.” DCVC led Twelve’s Series B financing, with participation from Series A lead investors Capricorn Technology Impact Fund and Carbon Direct Capital Management. Breakout Ventures, Munich Re Ventures, Elementum Ventures, and Microsoft Climate Innovation Fund also participated. In addition, Twelve secured a Series B and strategic program investment from the Chan Zuckerberg Initiative (CZI). “Carbon transformation has the potential to turn CO2 from a harmful waste stream into useful products for the global economy,” said Jonathan Goldberg, CEO of Carbon Direct. "With the costs of carbon capture, renewables and electrolyzers continuing to fall, Twelve’s technology stands to play a crucial role in decarbonizing some of the hardest-to-abate industries.” To help drive Twelve’s industrial scaleup, the company just announced additions of key industry veterans to its leadership team: Anne Roby, Independent Board Director and former Linde executive; David Frank, Chief Productization Officer and former Cummins director; and Ram Ramprasad, Chief Commercial Officer and former Linde executive. About Twelve Twelve is the carbon transformation company, a new kind of chemical company built for the climate era. We make essential products from air, not oil. Our groundbreaking technology eliminates emissions by transforming CO2 into critical chemicals, materials and fuels that today are made from fossil fuels. We call it carbon transformation, and it fundamentally changes how we can address climate change, reduce emissions and reverse the carbon imbalance. Reinventing what it means to be a chemical company, we’re on a mission to create a climate positive world and a fossil free future through the power of chemistry.

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CHEMICAL TECHNOLOGY

Wilbur-Ellis Partners with Guardian Agriculture in Multi-Million Dollar Agreement to Bring Autonomous Aerial Application to Growers Across America

Wilbur-Ellis | July 04, 2022

Guardian Agriculture, a leading innovator and developer of the first fully autonomous crop protection aircraft system, secured a multi-million-dollar partnership with Wilbur-Ellis, a leading marketer, distributor and manufacturer of agriculture products, specialty chemicals, and animal feed. The partnership will give Wilbur-Ellis customers an opportunity to access this state-of-the-art technology before anyone else. "This is the first new aerial technology to make a material impact on American farms. We believe it can be profitably and rapidly deployed and are looking forward to working with Guardian Ag to roll out their technology to our customers and partners," said Chief Executive Officer of Cavallo Ventures at Wilbur-Ellis, Mike Wilbur. Guardian Ag's fully electric vertical take-off and landing (eVTOL) aircraft system can safely and securely deliver precision application of crop protection in a fraction of the time and cost. The autonomous aircraft can carry multi-hundred-pound payloads and address a wide range of application spray volumes and application needs for growers. With four six-foot propellers and an overall 15-foot aircraft width, the eVTOL system efficiently covers 40 acres per hour of full-field crop protection to the grower. Designed and manufactured in the U.S. and combining an autonomous aircraft, a ground station supercharger, and software generating domestically stored data, the eVTOL systems offer on-target application to fields when and where necessary. Using industry standard nozzles, pressure, droplet sizes, and application volumes, Guardian's eVTOL aircraft systems are one of the most safe and cost-effective methods to deliver full-field application. "Guardian's technology delivers tremendous benefits to both growers and the environment," said Chief Executive Officer and co-founder of Guardian Ag, Adam Bercu. "Growers can expect a cost-effective application that will solve critical problems with coverage quality, sustainability, repeatability, and eliminate off-target spray and overspray," he said. With in-flight monitoring, measurement, and data collection capabilities, application variables are collected in real-time, including wind speed, temperature, obstructions, and more. Coupled with pre-planned flight plans, designated spray boundaries and spray rates, Guardian's systems will significantly reduce application errors by providing superior spray quality with reduced environmental and economic risk impacts. "Our autonomous systems deliver high-precision crop protection, enabling significant improvements in environmental safety for workers, soil health, and beneficial insect conservation," said Jeff Sparks, co-founder and Chief Operating Officer of Guardian Ag. Additionally, eVTOL systems are 100 percent electric and capable of reducing emissions by millions of pounds annually when compared to traditional application methods. "As the largest commercial commitment to agriculture robotics to date, this investment and partnership signify Wilbur-Ellis' dedication to delivering meaningful, impactful innovation and technology to growers across our footprint," said John Buckley, President and Chief Executive Officer of Wilbur-Ellis. Wilbur-Ellis' application business currently covers approximately five million acres annually. The eVTOL systems will support Wilbur-Ellis' strong aerial operations business throughout its large share of the aerial application market by adding eVTOL aircraft to its current helicopter and fixed-wing fleets. "We are excited to make an early investment in this technology, which is the only unmanned aerial application system available today, and we're even more excited to partner with Guardian to commercialize it and bring it to our customers," said John Kuhn, Director of Business Development at Wilbur-Ellis. Operating in strong collaboration, both companies have worked together over the last year to commercialize and bring American growers advanced technology that will have immediate positive impacts for their business. Guardian's regulatory approval process is well under way, with commercialization and availability to growers occurring in 2023. "Guardian's autonomy and powertrain technologies allow us to rapidly expand our product line to meet the needs of all American farmers," said Dan Cody, Guardian's Vice President of Software. With the Salinas Valley of California being eyed for potential first deployment of the eVTOL aircraft in 2023, Willie Negroni, Wilbur-Ellis Director of Sales, commented, "Guardian's aircraft solution complements our current aerial application business in the Salinas Valley and we see opportunity for customers, particularly around hard-to-spray areas, because eVTOL systems have the potential to provide a better application than what is currently available today." "It's always great to see a company Cavallo Ventures has invested in grow into a commercial partnership with one of Wilbur-Ellis' divisions, such as what we're seeing today with Guardian Ag and our Agribusiness Division. Over its 100-year history, Wilbur-Ellis has always been, and continues to be, a leader of technological and innovative advances that make real differences for our customers. Our venture capital arm, Cavallo Ventures, actively seeks out new and exciting opportunities. I'm excited to add more flexibility and choices for our customers." Mike Wilbur of Cavallo Ventures Mark Ripato, Wilbur-Ellis Agribusiness President, said: "EVTOL systems allow Wilbur-Ellis to give customers more options for precise application to acreage, helping growers make the best decisions about when and how they treat their crops. It's particularly exciting to expand our already successful aerial business with a technology that is new to the market and one that I feel will make a real difference for our growers' crop success and give them a positive return on the investment with us." Guardian Agriculture was co-founded by Adam Bercu and Jeff Sparks out of the need to make tangible, meaningful, positive impacts on the world with electric systems. Seeking to solve actual, everyday problems growers face, Guardian Ag is accelerating sustainable farming by providing access to precision application to all American farmers, dramatically improving crop protection, the environment, and the farmer's bottom line. "We're making the future that we dreamed of as children come to life by creating technology that will benefit the real world," said Guardian Ag's COO, Jeff Sparks. Guardian Ag has delivered the first-of-its-kind unmanned aerial crop application aircraft and Wilbur-Ellis is excited to commercialize this American-made solution and make it available to growers across the country. About Guardian Agriculture Guardian Agriculture accelerates sustainable farming by providing all farmers with precise, eVTOL-based aerial application. Proudly manufacturing in the U.S., our mission is to define a new age of crop protection — empowering growers and their partners to refine their chemical use and grow more with less. About the Wilbur-Ellis Companies Founded in 1921, the Wilbur-Ellis companies are leading international marketers, distributors and manufacturers of agricultural products, animal nutrients and specialty chemicals and ingredients. By developing strong relationships, making strategic market investments and capitalizing on new opportunities, the Wilbur-Ellis companies have continued to grow the business with sales of over $3 billion.

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CHEMICAL MANAGEMENT

Oberon Fuels Joins International Trade Associations

Oberon Fuels | July 01, 2022

Oberon Fuels a maker of products that reduce greenhouse gas emissions of major energy sectors, has joined both the World Biogas Association and Liquid Gas Europe as Oberon continues to build upon its work in Europe and around the world. Oberon has developed a straightforward ‘here-now’ way to slash the CO2 emissions of the global Liquefied Petroleum Gas industry through the production of renewable dimethyl ether. Because rDME can be stored, transported and dispensed using existing LPG vehicles and equipment, it can be readily blended with fossil LPG to reduce carbon emissions by up to 60 percent. The intersection between rDME made from biogas and the LPG industry is a key reason for Oberon to join these trade associations. The EU consumes about 48 billion liters of LPG per year, of which an estimated 3.8 billion liters (1 billion gallons) are imported from Russia. Oberon Fuels can enable European countries to produce fuels from local renewable biomass with no indirect land use impacts while reducing the need to import foreign energy resources. To help meet the goals of the EU Green Deal, the EU market is ready for new approaches to decarbonizing a range of major uses including transport, heating and agriculture. Oberon’s interest in expanding into Europe and other global markets is intended to accelerate commercial adoption of rDME with near-term market trials leading to deployment of multiple commercial-scale production plants. Oberon already has strategic collaborations with leaders around the world including Suburban Propane (US) and South America-based Lipigas. Oberon executives were in Switzerland recently presenting at the International DME Association’s annual event, and company CEO Rebecca Boudreaux, Ph.D., spoke earlier today at the European Liquid Gas Congress event in Barcelona. About Oberon Fuels California-based Oberon Fuels is on a mission to decarbonize the fuel and energy sectors through the commercialization of renewable dimethyl ether. Oberon’s low or carbon-negative rDME can reduce the carbon intensity of propane by up to 60 percent when blended, offering potential reductions in global CO2 of 750 million metric tons per year. rDME’s characteristics also makes it a compelling means for transporting hydrogen for its myriad, fast-growing applications.

Read More

CHEMICAL TECHNOLOGY

Twelve to Deploy World’s First Industrial-Scale Carbon Transformation Platform

Twelve | July 04, 2022

Twelve, the carbon transformation company, is announcing $130 million in Series B and additional funding to scale the engineering, manufacturing, and deployment of its industrial-scale carbon transformation technology for the creation of a wide range of products with a lower carbon footprint. Twelve’s carbon transformation technology converts captured CO2 into products historically made from fossil fuels. According to research from Columbia’s SIPA Center on Global Energy Policy, replacing fossil feedstocks in the production of chemicals, materials, and fuels with renewable carbon from point source or direct air capture could avoid nearly 10 percent of global greenhouse gas emissions. Twelve is currently transforming emissions into products for the automotive, household and apparel industries, as well as for government entities and global technology companies, by replacing petrochemicals and fossil-based transportation fuels with CO2Made® materials and carbon-neutral fuels like E-JetⓇ. “Companies and governments no longer need to rely on fossil fuels for the carbon that goes into everything from apparel and cleaning products to electronics and jet fuel. This fresh funding ensures we can reach industrial scale to help new and existing partners achieve rapid emissions-reduction.” Twelve Co-Founder and CEO Nicholas Flanders Twelve’s partners include Mercedes-Benz, Procter & Gamble, Shopify, the U.S. National Aeronautics and Space Administrationand the U.S. Air Force, all of which use Twelve’s breakthrough carbon transformation technology to reduce emissions and create CO2Made products. “As more companies and organizations adopt carbon-neutrality targets, they urgently need technologies like Twelve’s to rapidly green supply chains and corporate travel to reduce emissions at scale,” said Zachary Bogue, Managing Partner, DCVC. “Since leading Twelve’s seed round in 2018, we’ve only become more confident that their technology offers businesses a critical solution for not just offsetting emissions, but eliminating them.” The new funding follows Twelve’s first commercial products, a line of CO2Made sunglasses with sustainable fashion brand PANGAIA, and carbon-neutral sustainable aviation fuel (SAF), E-Jet. Twelve was recently recognized by Fast Company as the world’s #1 most innovative energy company of 2022 and as a BloombergNEF Pioneer in the Decarbonizing Aviation category. “Delivering low-carbon sustainable products consumers desire will require scaling innovative solutions such as Twelve’s carbon transformation technology.” said Todd Cline, Senior Director of Sustainability, for Procter & Gamble Fabric Care. “We’re glad to see Twelve given the opportunity to expand their opportunity to impact a broad variety of sustainable consumer products enabled by their technology.” “Twelve has the potential to disrupt petrochemical supply chains by creating a wide range of materials from carbon emissions instead of fossil fuels,” said Udo Gayer, Manager of New Business in Production Planning at Mercedes-Benz Cars. “The potential impact of their technology is immense, and I’m glad to see them receive the funding to continue scaling their technology.” DCVC led Twelve’s Series B financing, with participation from Series A lead investors Capricorn Technology Impact Fund and Carbon Direct Capital Management. Breakout Ventures, Munich Re Ventures, Elementum Ventures, and Microsoft Climate Innovation Fund also participated. In addition, Twelve secured a Series B and strategic program investment from the Chan Zuckerberg Initiative (CZI). “Carbon transformation has the potential to turn CO2 from a harmful waste stream into useful products for the global economy,” said Jonathan Goldberg, CEO of Carbon Direct. "With the costs of carbon capture, renewables and electrolyzers continuing to fall, Twelve’s technology stands to play a crucial role in decarbonizing some of the hardest-to-abate industries.” To help drive Twelve’s industrial scaleup, the company just announced additions of key industry veterans to its leadership team: Anne Roby, Independent Board Director and former Linde executive; David Frank, Chief Productization Officer and former Cummins director; and Ram Ramprasad, Chief Commercial Officer and former Linde executive. About Twelve Twelve is the carbon transformation company, a new kind of chemical company built for the climate era. We make essential products from air, not oil. Our groundbreaking technology eliminates emissions by transforming CO2 into critical chemicals, materials and fuels that today are made from fossil fuels. We call it carbon transformation, and it fundamentally changes how we can address climate change, reduce emissions and reverse the carbon imbalance. Reinventing what it means to be a chemical company, we’re on a mission to create a climate positive world and a fossil free future through the power of chemistry.

Read More

CHEMICAL TECHNOLOGY

Wilbur-Ellis Partners with Guardian Agriculture in Multi-Million Dollar Agreement to Bring Autonomous Aerial Application to Growers Across America

Wilbur-Ellis | July 04, 2022

Guardian Agriculture, a leading innovator and developer of the first fully autonomous crop protection aircraft system, secured a multi-million-dollar partnership with Wilbur-Ellis, a leading marketer, distributor and manufacturer of agriculture products, specialty chemicals, and animal feed. The partnership will give Wilbur-Ellis customers an opportunity to access this state-of-the-art technology before anyone else. "This is the first new aerial technology to make a material impact on American farms. We believe it can be profitably and rapidly deployed and are looking forward to working with Guardian Ag to roll out their technology to our customers and partners," said Chief Executive Officer of Cavallo Ventures at Wilbur-Ellis, Mike Wilbur. Guardian Ag's fully electric vertical take-off and landing (eVTOL) aircraft system can safely and securely deliver precision application of crop protection in a fraction of the time and cost. The autonomous aircraft can carry multi-hundred-pound payloads and address a wide range of application spray volumes and application needs for growers. With four six-foot propellers and an overall 15-foot aircraft width, the eVTOL system efficiently covers 40 acres per hour of full-field crop protection to the grower. Designed and manufactured in the U.S. and combining an autonomous aircraft, a ground station supercharger, and software generating domestically stored data, the eVTOL systems offer on-target application to fields when and where necessary. Using industry standard nozzles, pressure, droplet sizes, and application volumes, Guardian's eVTOL aircraft systems are one of the most safe and cost-effective methods to deliver full-field application. "Guardian's technology delivers tremendous benefits to both growers and the environment," said Chief Executive Officer and co-founder of Guardian Ag, Adam Bercu. "Growers can expect a cost-effective application that will solve critical problems with coverage quality, sustainability, repeatability, and eliminate off-target spray and overspray," he said. With in-flight monitoring, measurement, and data collection capabilities, application variables are collected in real-time, including wind speed, temperature, obstructions, and more. Coupled with pre-planned flight plans, designated spray boundaries and spray rates, Guardian's systems will significantly reduce application errors by providing superior spray quality with reduced environmental and economic risk impacts. "Our autonomous systems deliver high-precision crop protection, enabling significant improvements in environmental safety for workers, soil health, and beneficial insect conservation," said Jeff Sparks, co-founder and Chief Operating Officer of Guardian Ag. Additionally, eVTOL systems are 100 percent electric and capable of reducing emissions by millions of pounds annually when compared to traditional application methods. "As the largest commercial commitment to agriculture robotics to date, this investment and partnership signify Wilbur-Ellis' dedication to delivering meaningful, impactful innovation and technology to growers across our footprint," said John Buckley, President and Chief Executive Officer of Wilbur-Ellis. Wilbur-Ellis' application business currently covers approximately five million acres annually. The eVTOL systems will support Wilbur-Ellis' strong aerial operations business throughout its large share of the aerial application market by adding eVTOL aircraft to its current helicopter and fixed-wing fleets. "We are excited to make an early investment in this technology, which is the only unmanned aerial application system available today, and we're even more excited to partner with Guardian to commercialize it and bring it to our customers," said John Kuhn, Director of Business Development at Wilbur-Ellis. Operating in strong collaboration, both companies have worked together over the last year to commercialize and bring American growers advanced technology that will have immediate positive impacts for their business. Guardian's regulatory approval process is well under way, with commercialization and availability to growers occurring in 2023. "Guardian's autonomy and powertrain technologies allow us to rapidly expand our product line to meet the needs of all American farmers," said Dan Cody, Guardian's Vice President of Software. With the Salinas Valley of California being eyed for potential first deployment of the eVTOL aircraft in 2023, Willie Negroni, Wilbur-Ellis Director of Sales, commented, "Guardian's aircraft solution complements our current aerial application business in the Salinas Valley and we see opportunity for customers, particularly around hard-to-spray areas, because eVTOL systems have the potential to provide a better application than what is currently available today." "It's always great to see a company Cavallo Ventures has invested in grow into a commercial partnership with one of Wilbur-Ellis' divisions, such as what we're seeing today with Guardian Ag and our Agribusiness Division. Over its 100-year history, Wilbur-Ellis has always been, and continues to be, a leader of technological and innovative advances that make real differences for our customers. Our venture capital arm, Cavallo Ventures, actively seeks out new and exciting opportunities. I'm excited to add more flexibility and choices for our customers." Mike Wilbur of Cavallo Ventures Mark Ripato, Wilbur-Ellis Agribusiness President, said: "EVTOL systems allow Wilbur-Ellis to give customers more options for precise application to acreage, helping growers make the best decisions about when and how they treat their crops. It's particularly exciting to expand our already successful aerial business with a technology that is new to the market and one that I feel will make a real difference for our growers' crop success and give them a positive return on the investment with us." Guardian Agriculture was co-founded by Adam Bercu and Jeff Sparks out of the need to make tangible, meaningful, positive impacts on the world with electric systems. Seeking to solve actual, everyday problems growers face, Guardian Ag is accelerating sustainable farming by providing access to precision application to all American farmers, dramatically improving crop protection, the environment, and the farmer's bottom line. "We're making the future that we dreamed of as children come to life by creating technology that will benefit the real world," said Guardian Ag's COO, Jeff Sparks. Guardian Ag has delivered the first-of-its-kind unmanned aerial crop application aircraft and Wilbur-Ellis is excited to commercialize this American-made solution and make it available to growers across the country. About Guardian Agriculture Guardian Agriculture accelerates sustainable farming by providing all farmers with precise, eVTOL-based aerial application. Proudly manufacturing in the U.S., our mission is to define a new age of crop protection — empowering growers and their partners to refine their chemical use and grow more with less. About the Wilbur-Ellis Companies Founded in 1921, the Wilbur-Ellis companies are leading international marketers, distributors and manufacturers of agricultural products, animal nutrients and specialty chemicals and ingredients. By developing strong relationships, making strategic market investments and capitalizing on new opportunities, the Wilbur-Ellis companies have continued to grow the business with sales of over $3 billion.

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