Chemical Security: Toxic Chemicals of Security Concern

PricewaterhouseCoopers Australia (PwC) has been engaged by Attorney-General’s Department (AGD) to prepare this Decision Regulatory Impact Statement (RIS) examining the proposed measures to enhance chemical security in relation to 84 toxic chemicals of security concern. These include a variety of industrial and agricultural/veterinary chemicals.

Spotlight

Concert Pharmaceuticals, Inc.

Concert Pharmaceuticals is a clinical stage biopharmaceutical company focused on applying its DCE Platform® (deuterated chemical entity platform) to create novel small molecule drugs. This approach starts with approved drugs in which deuterium substitution has the potential to enhance clinical safety, tolerability or efficacy. The Company is developing a broad pipeline of innovative medicines targeting autoimmune and inflammatory diseases and central nervous systems (CNS) disorders.

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Chemical Technology

The supply-chain inflation threat to petrochemicals demand

Article | July 14, 2022

Petrochemicals themselves remain in short supply. This is partly because of reduced feedstock from refineries, a consequence of the pandemic-related collapse in transportation fuels demand.Global petrochemical supply is still edging back to something like normal following the US winter storms in February, during which most US capacity was shut down. A point of discussion is whether containers will become available in the right places at the right prices to relieve tightness in the European polyethylene (PE) market, once US supply has normalised. The container issue is making it difficult to move PE and polypropylene (PP) cargoes from Asia to Europe.Market intelligence from the US-based ICIS CDI team indicates that enough container freight space will be available to resume significant shipments of US PE to Europe, albeit at high prices. It will be several more weeks before domestic pipelines have been refilled, enabling US producers to refocus on exports, added CDI.

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Chemical Technology

THE BENEFITS OF CHEMICAL FOAMERS, AND HOW BEST TO USE THEM TO MAXIMISE PRODUCTION

Article | August 2, 2022

Downhole fluid build-up coupled with a drop in reservoir pressure can lead to the rapid decline of gas production rates, and can ultimately result in a well ceasing production. While there are many ways to deliquify a well to maximise production, chemical foamers can be incredibly effective and well worth considering. In this blog post, Kevin Lonie shares some of the benefits of using chemical foamers, and provides insights and advice around how best to use them… “Foamers are a much cheaper option than alternative solutions, such as mechanical lifts, and there is very little risk associated with their usage. If a foamer doesn’t work, it won’t make the well worse - so often we see clients giving them a go before opting for more expensive methods, in the hope that they produce the desired results. And we have seen their success over and over again.”

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Chemical Management

Developing pre-rig solutions that are greener, safer and more efficient

Article | July 14, 2022

MAY 2021 ///Vol 242 No. 5 FEATURES Developing pre-rig solutions that are greener, safer and more efficient There is an increased focus in the oil and gas sector to look further afield to opportunities presented in deepwater locations. Because of this, finding cost-efficient solutions and overcoming the associated challenges that arise below 1,000 ft will be vital for the success of new activity. Jostein Aleksandersen, Neodrill There is an increased focus in the oil and gas sector to look further afield to opportunities presented in deepwater locations. Because of this, finding cost-efficient solutions and overcoming the associated challenges that arise below 1,000 ft will be vital for the success of new activity. All those currently—and those considering—operating in deepwater fields will have an awareness of the general challenges that are presented at such depths. From considerations relating to vast increases in pressure, to the potential for increased drilling time and days spent offshore, there are several hurdles that follow when operating in what are often challenging well environments. In addition, suitable solutions also must support the industry drive to reduce emissions by offering a more carbon-efficient approach.

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Chemical Technology

Reimagining the Workforce with Anglo American

Article | June 21, 2021

“At Anglo-American, we’re really focused on finding the best ways to attract the most talented people in the industry and effectively equipping our existing workforce based on what they need today and what the future will mean for their careers. We’re also committed to providing learning opportunities that lead to growth and development in the communities in which we operate. Our people are a strategic advantage. We want to ensure that continues to be the case as the mining industry evolves and faces more disruption.

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Spotlight

Concert Pharmaceuticals, Inc.

Concert Pharmaceuticals is a clinical stage biopharmaceutical company focused on applying its DCE Platform® (deuterated chemical entity platform) to create novel small molecule drugs. This approach starts with approved drugs in which deuterium substitution has the potential to enhance clinical safety, tolerability or efficacy. The Company is developing a broad pipeline of innovative medicines targeting autoimmune and inflammatory diseases and central nervous systems (CNS) disorders.

Related News

US, Canada outline plans to align hazcom standards

Chemical Watch | March 11, 2020

Regulators from the US and Canada have laid out plans to coordinate efforts on workplace hazard communication standards as the two countries implement updates to the UN's Globally Harmonized System of classification and labelling of chemicals (GHS). According to the US-Canada Regulatory Cooperation Council (RCC) 2019-20 workplan, released this week, the council expects to roll out joint guidance on the implementation of GHS and interpreting requirements for safety data sheets (SDSs) and communicating product hazards across the two jurisdictions. Another primary goal, highlighted in the RCC workplan, is to have "one label and one SDS" that is acceptable in both countries. US and Canadian regulators also will continue to work together to push for a common position on the GHS at future UN meetings and plan to hold a stakeholder meeting this summer.

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Protecting people from chemical hazards — another EPA failure in the making

TheHill | November 25, 2019

Most Americans assume that the chemicals in the consumer products we buy, such as that long list of unpronounceable ingredients in your bathroom cleaner or laundry detergent, have been tested and found safe for people and the environment. The truth is, not so much. And Trump’s Environmental Protection Agency (EPA) is missing an important opportunity to make those products safer. For decades, efforts to ensure chemical safety were stymied by an ineffective regulatory regime: the Toxic Substances Control Act (TSCA) of 1976, which regulated household and industrial compounds, was widely regarded as toothless. During my 20-plus year career at EPA, I served as a senior manager in the agency’s toxics program from 1987 to 1989. The weakness of the original TSCA was a key factor in my decision to leave that position.

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Tiny gels sop up intestinal toxins

phys.org | March 20, 2018

Bacterial infections that target the intestine can cause conditions that range from uncomfortable to deadly. While it's easy to blame the bacteria, it's actually the toxins the bacteria produce that trigger inflammation, diarrhea, fever and cramps. Treatment strategies typically include indiscriminate antibiotics that slaughter health-promoting gut bacteria along with disease-causing microbes. Researchers now report the development of a microgel scavenger that targets toxins instead of bacteria. The researchers will present their work today at the 255th National Meeting & Exposition of the American Chemical Society (ACS)."We want to develop a new therapy that is based on scavenging the toxins rather than killing both the good and bad bacteria," says Alexander Kuehne, Ph.D. "This way inflammation can be reduced while supporting the natural intestinal flora and holding the bad bacteria at bay."About three decades ago, Kuehne says, scientists developed a particle that used electronic charge to bind toxins in the intestine. It made it to the clinical testing stage, he says, but had too many non-specific targets for further development. This idea was the basis, though, for Kuehne's team's current project.

Read More

US, Canada outline plans to align hazcom standards

Chemical Watch | March 11, 2020

Regulators from the US and Canada have laid out plans to coordinate efforts on workplace hazard communication standards as the two countries implement updates to the UN's Globally Harmonized System of classification and labelling of chemicals (GHS). According to the US-Canada Regulatory Cooperation Council (RCC) 2019-20 workplan, released this week, the council expects to roll out joint guidance on the implementation of GHS and interpreting requirements for safety data sheets (SDSs) and communicating product hazards across the two jurisdictions. Another primary goal, highlighted in the RCC workplan, is to have "one label and one SDS" that is acceptable in both countries. US and Canadian regulators also will continue to work together to push for a common position on the GHS at future UN meetings and plan to hold a stakeholder meeting this summer.

Read More

Protecting people from chemical hazards — another EPA failure in the making

TheHill | November 25, 2019

Most Americans assume that the chemicals in the consumer products we buy, such as that long list of unpronounceable ingredients in your bathroom cleaner or laundry detergent, have been tested and found safe for people and the environment. The truth is, not so much. And Trump’s Environmental Protection Agency (EPA) is missing an important opportunity to make those products safer. For decades, efforts to ensure chemical safety were stymied by an ineffective regulatory regime: the Toxic Substances Control Act (TSCA) of 1976, which regulated household and industrial compounds, was widely regarded as toothless. During my 20-plus year career at EPA, I served as a senior manager in the agency’s toxics program from 1987 to 1989. The weakness of the original TSCA was a key factor in my decision to leave that position.

Read More

Tiny gels sop up intestinal toxins

phys.org | March 20, 2018

Bacterial infections that target the intestine can cause conditions that range from uncomfortable to deadly. While it's easy to blame the bacteria, it's actually the toxins the bacteria produce that trigger inflammation, diarrhea, fever and cramps. Treatment strategies typically include indiscriminate antibiotics that slaughter health-promoting gut bacteria along with disease-causing microbes. Researchers now report the development of a microgel scavenger that targets toxins instead of bacteria. The researchers will present their work today at the 255th National Meeting & Exposition of the American Chemical Society (ACS)."We want to develop a new therapy that is based on scavenging the toxins rather than killing both the good and bad bacteria," says Alexander Kuehne, Ph.D. "This way inflammation can be reduced while supporting the natural intestinal flora and holding the bad bacteria at bay."About three decades ago, Kuehne says, scientists developed a particle that used electronic charge to bind toxins in the intestine. It made it to the clinical testing stage, he says, but had too many non-specific targets for further development. This idea was the basis, though, for Kuehne's team's current project.

Read More

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