Application of Chromatography in Various Industries is Changing the Game!

Debashree Kabi | August 8, 2022 | 847 views | Read Time : 03:00 min

Application of
Used to separate and analyze compounds into their various components— chromatography plays a crucial part not just in the food industry but in the realms of drug testing, forensics, and even quality control in our favourite alcoholic drinks as well.

Advanced Chromatography is an analytical technique introduced to the world by chromatography instrument companies to separate and analyze individual chemicals from complex compounds. Recent developments in the biotechnology and pharma industries have created a significant surge in the chromatography market.

Read on to find out five fascinating facts about the day-to-day applications of chromatography in various industries and why businesses are looking to invest more in OEM chromatography manufacturing.

Why are Industry-Decision Makers Adapting to Chromatography?


Liquid Chromatography; A Popular Choice in Drug Testing

Today, a lot of drug tests use liquid chromatography-mass spectrometry because it is easy to use, widely available, and gives quick results. LC and LC-MS can be done in almost any testing facility, which is different from other methods. It can be run by people with little training, so a testing facility can hire mostly technicians instead of highly trained scientists, who are harder to find. LC-MS is also very accurate, which means that there are fewer false positives.

With liquid chromatography, you can get results in about 10 to 30 minutes, which is very fast. This technology is used by many drug testing labs across the country. It is widely used and trusted for testing drug samples and many other things.

Businesses associated with the sports industry are leveraging chromatography to effectively and accurately test athletes for doping or performance-enhancing drugs.

Use of HPCL in Pharmaceutical Industries

Chromatography is used in the medical and pharmaceutical industries to create vaccines. In addition, chromatography can determine which antibodies best neutralize viruses and diseases.

Mapp Biopharmaceutical, Inc. used the chromatography technique to develop the experimental immunization Zmapp to counteract the deadly Ebola virus. And it is still being used today to fight the coronavirus.

The pharmaceutical industry has gained enormous success by exclusively using HPLC to obtain precise results during drug trials. The results can be used to analyze finished drug products and their ingredients quantitatively and qualitatively during manufacturing.

The Detector in Forensic Science

Chromatography methods are a well-established, powerful suite of methodologies in forensic science, from drug busts, murders, and robberies, to the identification of a plethora of chemical compounds that may be present in samples from terrorist incidents.

Forensics use gas chromatography to help solve crimes. It helps analyze blood and clothing samples, allowing forensic scientists to investigate who and what was present at a crime scene.

In particular instances, chromatography can even help forensic scientists pinpoint the exact whereabouts of the alleged perpetrator and victim before the crime happened. It’s an error-free process. Therefore, it is incredibly helpful in court.

Additionally, chromatography is extremely handy in arson investigations. Most fires have a virtual cocktail of different substances. Every compound and substance differs in size and weight. Chromatography helps break down these varying compounds and substances to help determine what exactly started the fire.


Liquid Chromatography in Food Industry

Liquid chromatography plays a vital role in the food industry nowadays. It absolves and permits the selective removal of a wide variety of flavor and non-flavor-active food ingredients.

The USDA, along with other countries, has prioritized rigorous testing of processed meat's contents. For example, in 2013, it was found that horsemeat was being sold as beef without anyone noticing. As a result, the food industry decided to change its analytical techniques.

Chromatography quickly became the best way to find out what was in processed meats. High-Performance Liquid Chromatography and mass spectrometry were used to ensure that meat labeled beef was actually beef. In addition, it could tell if horse meat was mixed in with the beef, which helped keep people safe.

Bio-Rad Fast Acid Analysis Column in Beverage Testing

Not just food, many beverage manufacturers also use chromatography to ensure that each bottle of their product is the same. But, again, consistent taste is the main priority. And knowing the exact content of each bottle is the most proactive way to measure things.

The Bio-Rad fast acid analysis column has been successfully used by many companies to quantitatively determine vitamin C in juices, fresh drinks, and powdered drinks.

Chromatography Market is Opening New Dimensions in Various Businesses

Undoubtedly, technological advancement has created a vigorous need for chromatography devices. According to Verified Market Research, growing at a CAGR of 3.4% from 2020 to 2027, the chromatography market is projected to reach USD 4.73 billion by 2027.

The chromatography instrumentation market is currently witnessing huge advancements in the design of columns. This is raising the demand for development of better analytical reagents and resins. Increasing collaborations among the existing players, specifically in the Asian market is another propelling factor for this market. Additionally, emergence of green chromatography, increasing usage of chromatography instruments for monoclonal antibody purification, and usage of nanomaterial in chromatography are also fuelling the growth of this market. Plus, increased government funding in research and development activities is further driving the market growth.

With various pharmaceutical and biotechnology companies, chemical, food and beverage, and other industries contributing to its market growth, one thing is for sure— the increase in the chromatography system market is here to stay.

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"Interzero and Eastman are committed to reducing plastic waste and creating circularity through collaboration and innovation," said Brad Lich, Eastman executive vice president and chief commercial officer. "This agreement marks an important milestone towards Eastman's investment in France. We are happy to build a strong collaboration in Europe with Interzero to provide a portion of the feedstock needed to successfully operate our facility. The collaboration reinforces the complementary nature of mechanical and molecular recycling, and the importance of working together to create true circularity." Eastman's proven polyester renewal technology provides true circularity for hard-to-recycle plastic waste that remains in a linear economy today. This material is typically incinerated because it either cannot be mechanically recycled or must be downcycled using existing technology. Eastman's chemical recycling technology allows this hard-to-recycle waste to be broken down into its molecular building blocks and then reassembled to become first-quality material without any compromise in performance. Eastman's polyester renewal technology enables the potentially infinite value of materials by keeping them in production, lifecycle after lifecycle. With the technology's inherent efficiencies and the renewable energy sources available in France, materials can be produced with significantly less greenhouse gas emissions than traditional methods. About Interzero Interzero is an innovation leader in plastics recycling with the largest sorting capacity in Europe and one of the leading environmental service providers in the field of closing product, material, and logistics cycles. Under the guiding principle of "zero waste solutions", the company advises over 20,000 customers throughout Europe on the responsible handling of recyclable materials, thus helping them to improve their own sustainability performance and conserve primary resources. With about 2,000 employees, the company achieves a turnover of over one billion euros (2021). In 2020 alone Interzero saved 1.4 million tonnes of greenhouse gases compared to primary production and at the same time 12.3 million tonnes of primary raw materials through its recycling activities. About Eastman Founded in 1920, Eastman is a global specialty materials company that produces a broad range of products found in items people use every day. With the purpose of enhancing the quality of life in a material way, Eastman works with customers to deliver innovative products and solutions while maintaining a commitment to safety and sustainability. The company's innovation-driven growth model takes advantage of world-class technology platforms, deep customer engagement, and differentiated application development to grow its leading positions in attractive end markets such as transportation, building and construction, and consumables. As a globally inclusive and diverse company, Eastman employs approximately 14,000 people around the world and serves customers in more than 100 countries. The company had 2021 revenues of approximately $10.5 billion and is headquartered in Kingsport, Tennessee, USA. In Europe, Middle East and Africa (EMEA), Eastman employs approximately 2100 and is present in 10 countries. EMEA accounted for 26 percent of Eastman's total sales revenue in 2021.

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